{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T21:18:51Z","timestamp":1775855931662,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2020,7,5]],"date-time":"2020-07-05T00:00:00Z","timestamp":1593907200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabet. Med."],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>To estimate the rate at which people with diabetes and a low risk of foot ulceration change diabetic foot ulceration risk status over time, and to estimate the rate of ulceration, amputation and death among this population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted an observational study of 10 421 people with diabetes attending foot screening in an outpatient setting in NHS Fife, UK, using routinely collected data from a national diabetes register, NHS SCI Diabetes. We estimated the proportion of people who changed risk status and the cumulative incidence of ulceration, amputation and death, respectively, among people with diabetes at low risk of diabetic foot ulceration at 2\u2010year follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At 2\u2010year follow\u2010up, 5.1% (95% CI 4.7, 5.6) of people with diabetes classified as low risk at their first visit had progressed to moderate risk. The cumulative incidence of ulceration, amputation and death was 0.4% (95% CI 0.3, 0.6), 0.1% (95% CI 0.1, 0.2) and 3.4% (95% CI 3.1, 3.8), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>At 2\u2010year follow\u2010up, 5% of people at low risk of diabetic foot ulceration changed clinical risk status and &lt;1% of people experienced foot ulceration or amputation. These findings provide information which will help to inform the current debate regarding optimal foot screening intervals.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dme.14339","type":"journal-article","created":{"date-parts":[[2020,6,8]],"date-time":"2020-06-08T13:50:38Z","timestamp":1591624238000},"page":"2116-2123","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Complication rate among people with diabetes at low risk of foot ulceration in Fife, UK: an analysis of routinely collected data"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7396-4773","authenticated-orcid":false,"given":"R.","family":"Heggie","sequence":"first","affiliation":[{"name":"Health Economics and Health Technology Assessment, Institute of Health and Wellbeing University of Glasgow Glasgow"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7742-1757","authenticated-orcid":false,"given":"F.","family":"Chappell","sequence":"additional","affiliation":[{"name":"Usher Institute, University of Edinburgh Edinburgh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0473-9959","authenticated-orcid":false,"given":"F.","family":"Crawford","sequence":"additional","affiliation":[{"name":"School of Medicine University of St Andrews Fife"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Martin","sequence":"additional","affiliation":[{"name":"NHS Fife, Queen Margaret Hospital Dunfermline"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2643-626X","authenticated-orcid":false,"given":"S.","family":"Gupta","sequence":"additional","affiliation":[{"name":"NHS Fife, Queen Margaret Hospital Dunfermline"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3199-221X","authenticated-orcid":false,"given":"N.","family":"Hawkins","sequence":"additional","affiliation":[{"name":"Health Economics and Health Technology Assessment, Institute of Health and Wellbeing University of Glasgow Glasgow"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7621-2462","authenticated-orcid":false,"given":"M.","family":"Horne","sequence":"additional","affiliation":[{"name":"Usher Institute, University of Edinburgh Edinburgh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0570-5678","authenticated-orcid":false,"given":"G. P.","family":"Leese","sequence":"additional","affiliation":[{"name":"NHS Tayside Dundee"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3811-8165","authenticated-orcid":false,"given":"J.","family":"Lewsey","sequence":"additional","affiliation":[{"name":"Health Economics and Health Technology Assessment, Institute of Health and Wellbeing University of Glasgow Glasgow"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,7,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-018-4723-y"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/dme.13973"},{"key":"e_1_2_8_4_1","unstructured":"National Institute for Health and Care Excellence (NICE).Diabetic foot problems: prevention and management. Available athttps:\/\/www.nice.org.uk\/guidance\/ng19\/resources\/diabetic\u2010foot\u2010problems\u2010prevention\u2010and\u2010management\u2010pdf\u20101837279828933 2015. Last accessed 16 November 2019."},{"key":"e_1_2_8_5_1","unstructured":"Management of diabetes.A National Clinical Guideline (SIGN 116). Available athttps:\/\/www.sign.ac.uk\/assets\/sign116.pdf 2010. Last accessed 16 November 2019."},{"key":"e_1_2_8_6_1","unstructured":"IWGDF.Practical Guidelines on the prevention and management of diabetic foot disease. Available athttps:\/\/iwgdfguidelines.org\/wp\u2010content\/uploads\/2019\/05\/01\u2010IWGDF\u2010practical\u2010guidelines\u20102019.pdf 2019. 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