{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T16:43:25Z","timestamp":1792428205188,"version":"4.5.0"},"reference-count":30,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,12,12]],"date-time":"2020-12-12T00:00:00Z","timestamp":1607731200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007605","name":"Aarhus Universitet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007605","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009708","name":"Novo Nordisk Fonden","doi-asserted-by":"publisher","award":["NNF14OC0011633"],"award-info":[{"award-number":["NNF14OC0011633"]}],"id":[{"id":"10.13039\/501100009708","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabet Med"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To estimate the incidence of falls in individuals with type 2 diabetes compared to healthy controls and to describe the characteristics of fallers with type 2 diabetes in relation to motor dysfunction, postural instability and diabetic polyneuropathy (DPN).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a cross\u2010sectional study of individuals with type 2 diabetes with DPN (<jats:italic>n<\/jats:italic>\u00a0=\u00a054), without DPN (<jats:italic>n<\/jats:italic>\u00a0=\u00a038) and healthy controls (<jats:italic>n<\/jats:italic>\u00a0=\u00a039). Falls were recorded within the preceding year. DPN was defined by clinical scores and nerve conduction studies. Motor function was assessed by a 6\u2010min walk test (6\u00a0MWT), five\u2010time sit\u2010to\u2010stand test (FTSST) and isokinetic dynamometry at the non\u2010dominant ankle and knee. An instability index (ST) was measured using static posturography. Univariate and bivariate descriptive statistics were used for group comparisons.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Compared with healthy controls, individuals with diabetes had a higher incidence of falls 36%, (<jats:italic>n<\/jats:italic>\u00a0=\u00a033) versus 15%, (<jats:italic>n<\/jats:italic>\u00a0=\u00a06), <jats:italic>p<\/jats:italic>\u00a0=\u00a00.02. There were no differences in falls when comparing individuals with and without DPN. Fallers had an impaired 6\u00a0MWT versus non\u2010fallers (450\u00a0\u00b1\u00a0153\u00a0m vs. 523\u00a0\u00b1\u00a097\u00a0m respectively), a slower FTSST (11.9\u00a0\u00b1\u00a04.2\u00a0s vs. 10.3\u00a0\u00b1\u00a02.9\u00a0s respectively) and a higher ST (53\u00a0\u00b1\u00a029 vs. 41\u00a0\u00b1\u00a017 respectively), <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.02 for all.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Individuals with type 2 diabetes reported a higher number of falls within the preceding year compared to healthy controls, irrespective of the presence of DPN. The main factors associated with falls were increased postural instability, lower walking capacity and slower sit\u2010to\u2010stand movements. The 6\u00a0MWT, FTSST and posturography should be considered in future screening programs in identification of individuals at risk for falls.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dme.14470","type":"journal-article","created":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T23:53:31Z","timestamp":1606866811000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Falls in individuals with type 2 diabetes; a cross\u2010sectional study on the impact of motor dysfunction, postural instability and diabetic polyneuropathy"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1288-6227","authenticated-orcid":false,"given":"Karolina S.","family":"Khan","sequence":"first","affiliation":[{"name":"Department of Neurology Aarhus University Hospital Aarhus Denmark"},{"name":"Faculty of Health Aarhus University Aarhus 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