{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T18:10:18Z","timestamp":1772129418816,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,3,6]],"date-time":"2021-03-06T00:00:00Z","timestamp":1614988800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007028","name":"Leona M. and Harry B. Helmsley Charitable Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007028","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabet Med"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Eritrea has no data on type 1 diabetes incidence in children and youth; therefore, a study was undertaken to determine this in persons aged &lt;25\u00a0years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data were collected on new type 1 diabetes diagnoses during 2019, from district, provincial and national hospitals. Type 1 diabetes was diagnosed according to standard WHO criteria. No secondary ascertainment source was available. 95% confidence intervals were computed based on approximation to the Poisson distribution, and age and gender effects were analysed with Poisson regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 532 new cases of type 1 diabetes. Mean \u00b1 standard deviation (range) age of diagnosis was 16.2\u00a0\u00b1\u00a05.7 (1.5\u201324.9) years, and peak age group was 15\u201319\u00a0years (n\u00a0=\u00a0200, 37.6%), with mode at 18\u00a0years. Incidence &lt;15\u00a0years was 11.5\/100,000 individuals [9.9\u201313.2], with the highest incidence in the 10\u201314\u00a0years group (19.0\/100,000 [15.5\u201323.1]). Incidence then peaked in the 15\u201319\u00a0years age group (50.2\/100,000 [43.5\u201357.7]) and remained high in the 20\u201324\u00a0years group (46.2\/100,000 [39.0\u201354.3]). There was a male:female ratio of 1.37 (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.001). Two hundred and thirty\u2010eight (44.7%) presented in diabetic ketoacidosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Type 1 diabetes incidence in Eritrea is moderate &lt;15\u00a0years, and high 15\u201324\u00a0years. The 15\u201319 and 20\u201324\u00a0years rates appear to be the highest published to date. Given the study was only for one\u00a0year, further confirmatory prospective information will clarify the situation and document trends. Assessment of the type 1 diabetes phenotypes that are occurring in Eritrea is also indicated.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dme.14544","type":"journal-article","created":{"date-parts":[[2021,2,15]],"date-time":"2021-02-15T19:38:56Z","timestamp":1613417936000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["High incidence of type 1 diabetes in adolescents and young adults in Eritrea"],"prefix":"10.1111","volume":"38","author":[{"given":"Goitom","family":"Mebrahtu","sequence":"first","affiliation":[{"name":"Eritrean National Diabetic Association Asmara Eritrea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jayanthi","family":"Maniam","sequence":"additional","affiliation":[{"name":"Life for a Child Program, Diabetes NSW &amp; ACT Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3928-9206","authenticated-orcid":false,"given":"Steven","family":"James","sequence":"additional","affiliation":[{"name":"University of the Sunshine Coast Petrie Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2022-0866","authenticated-orcid":false,"given":"Graham D.","family":"Ogle","sequence":"additional","affiliation":[{"name":"Life for a Child Program, Diabetes NSW &amp; ACT Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,3,6]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"United Nations.Least Developed Country Category: Eritrea Profile.2018.https:\/\/www.un.org\/development\/desa\/dpad\/least\u2010developed\u2010country\u2010category\u2010eritrea.html. 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Eritrea.2016.https:\/\/www.census.gov\/data\u2010tools\/demo\/idb\/metadata.php?R=Least%20Developed%20Countries&C=Eritrea#:~:text=1984%20census%20of%20Ethiopia%2C%20subnational present%2Dday%20Eritrea%20for%201980. accessed 2nd September 2020."},{"key":"e_1_2_10_8_1","unstructured":"United Nations.World population prospects: The 2019 revision (medium variant).https:\/\/population.un.org\/wpp\/.2019. 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