{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:27:54Z","timestamp":1753878474496,"version":"3.41.2"},"reference-count":32,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,9,11]],"date-time":"2022-09-11T00:00:00Z","timestamp":1662854400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabet Med"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>To test whether breastfeeding during the oral glucose tolerance test (OGTT) affects glucose and insulin outcomes (main outcome: 120\u2009min plasma glucose).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A randomized crossover trial was conducted in 20 women with prior gestational diabetes mellitus. Each woman undertook two OGTTs in the first 3\u2009months after delivery, breastfeeding the infant in one and avoiding breastfeeding in the other. Glucose and insulin were measured at 0, 30, 60 and 120\u2009min. Statistics included: T\u2010test for paired data, general linear model (GLM) for repeated measures. Analysis of covariance (ANCOVA) was used to adjust for glucose and insulin values at 0\u2009min. Statistical dispersion for GLM and ANCOVA outcomes is expressed as standard error.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the OGTTs with breastfeeding, higher values were observed for overall glucose and insulin concentrations, glucose and insulin peaks and individual time points of glucose (at 0, 30 and 60\u2009min) and insulin (at 0 and 60\u2009min) but without differences at 120\u2009min (glucose 6.7\u2009\u00b1\u20090.3 vs. 6.9\u2009\u00b1\u20090.3\u2009mmol\/L, <jats:italic>p<\/jats:italic>\u00a0=\u20090.506). The rate of abnormal tests was not different. ANCOVA confirmed higher postchallenge glucose values in the OGTT with breastfeeding and similar glucose values at 120\u2009min.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>According to the results of this randomized trial, we conclude that breastfeeding during the OGTT resulted in similar 120\u2009min glucose concentration and glycaemic status categorization. However, breastfeeding during the OGTT led to clear differences in glucose and insulin values in the first hour, that warrant further studies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dme.14954","type":"journal-article","created":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T03:14:40Z","timestamp":1662088480000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Breastfeeding effect on glucose tolerance assessment in women with previous gestational diabetes mellitus: A randomized controlled trial"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3390-9179","authenticated-orcid":false,"given":"Gabriela","family":"Monroy","sequence":"first","affiliation":[{"name":"Department of Endocrinology and Nutrition Parc Sanitari Sant Joan de D\u00e9u  Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5205-7680","authenticated-orcid":false,"given":"Cristina","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Nutrition Parc Sanitari Sant Joan de D\u00e9u  Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa","family":"Caball\u00e9","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Parc Sanitari Sant Joan de D\u00e9u  Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Altimira","sequence":"additional","affiliation":[{"name":"Clinical Biochemistry Laboratory Parc Sanitari Sant Joan de D\u00e9u  Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5055-6814","authenticated-orcid":false,"given":"Rosa","family":"Corcoy","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Nutrition Hospital de la Santa Creu i Sant Pau  Barcelona Spain"},{"name":"Department of Medicine Universitat Aut\u00f2noma de Barcelona  Barcelona Spain"},{"name":"Biomedical Research Center Network of Bioengineering, Biomaterials and Nanomedicine (CIBERBBN), ISCIII  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,9,11]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60731-5"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc22-S015"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcjd.2017.10.038"},{"issue":"2","key":"e_1_2_11_5_1","first-page":"45","article-title":"Care of pregnancies complicated by diabetes. 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