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It is further characterised by widespread social stigma, judgement and paternalism. This physical, social and psychological burden collectively influences self\u2010management behaviours. It is widely recognised that the individual's perspective about the impact of trying to manage the disease and the burden that self\u2010management confers must be addressed to achieve optimal health outcomes. Standardised, rigorous assessment of mental and behavioural health status, in interaction with physical health outcomes is crucial to aid understanding of person\u2010reported outcomes (PROs). Whilst tempting to conceptualise PROs as an issue of perceived quality of life (QoL), in fact health\u2010related QoL is multi\u2010dimensional and covers indicators of physical or functional health status, psychological and social well\u2010being. This complexity is illuminated by the large number of person reported outcome measures (PROMs) that have been developed across multiple psychosocial domains. 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