{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T03:12:18Z","timestamp":1771902738771,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T00:00:00Z","timestamp":1714003200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabet Med"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>To describe trends in risk factor control and serious hypoglycaemia in people with type 1 diabetes and to assess the effect of starting continuous glucose monitoring (CGM) in the real\u2010world setting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Two cross\u2010sectional surveys including 5746 individuals in 2012 and 18,984 individuals in 2020 based on data recorded in the Norwegian Diabetes Register for Adults (NDR\u2010A) and an analysis of a longitudinal cohort of 2057 individuals where data on CGM and HbA1c were available in the NDR\u2010A in 2012 and 2020.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the cross\u2010sectional surveys mean HbA1c decreased from 66\u2009mmol\/mol (99% CI 65, 66) (8.2%) in 2012 to 61\u2009mmol\/mol (99% CI 61, 61) (7.7%) in 2020 (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001). The proportion reporting serious hypoglycaemia decreased from 16.9 to 6.2% in 2020 (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001). Mean LDL\u2010cholesterol decreased from 2.80 (99% CI 2.78, 2.83) to 2.63 (99% CI 2.61, 2.65) mmol\/l in 2020 (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001). Mean blood pressure increased slightly. In the CGM cohort, we found a 3\u2009mmol\/mol (0.3%) greater improvement in mean HbA1c and a greater reduction in serious hypoglycaemia (\u221212.3% vs. \u22126.2%) among individuals that had started using CGM between 2013 and 2020 when compared with individuals that had not started using CGM.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Between 2012 and 2020, we found marked improvements in glycaemic control and a considerable decrease in the proportion of individuals reporting serious hypoglycaemia. The proportion of individuals using CGM increased substantially and individuals that had started using CGM by 2020 showed greater improvement in glycaemic control and less serious hypoglycaemia.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dme.15335","type":"journal-article","created":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T16:49:31Z","timestamp":1714063771000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["A register\u2010based study describing time trends in risk factor control and serious hypoglycaemia together with the effects of starting continuous glucose monitoring in people with type 1 diabetes in Norway"],"prefix":"10.1111","volume":"41","author":[{"given":"Una \u00d8rvim","family":"S\u00f8lvik","sequence":"first","affiliation":[{"name":"Department of Global Public Health and Primary Care University of Bergen  Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John Graham","family":"Cooper","sequence":"additional","affiliation":[{"name":"Norwegian Diabetes Register for Adults, Norwegian Organization for Quality Improvement of Laboratory Examinations (Noklus) Haraldsplass Deaconess Hospital  Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karianne Fjeld","family":"L\u00f8vaas","sequence":"additional","affiliation":[{"name":"Norwegian Diabetes Register for Adults, Norwegian Organization for Quality Improvement of Laboratory Examinations (Noklus) Haraldsplass Deaconess Hospital  Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tony","family":"Ernes","sequence":"additional","affiliation":[{"name":"Norwegian Diabetes Register for Adults, Norwegian Organization for Quality Improvement of Laboratory Examinations (Noklus) Haraldsplass Deaconess Hospital  Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tone Vonheim","family":"Madsen","sequence":"additional","affiliation":[{"name":"Norwegian Diabetes Register for Adults, Norwegian Organization for Quality Improvement of Laboratory Examinations (Noklus) Haraldsplass Deaconess Hospital  Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sverre","family":"Sandberg","sequence":"additional","affiliation":[{"name":"Norwegian Diabetes Register for Adults, Norwegian Organization for Quality Improvement of Laboratory Examinations (Noklus) Haraldsplass Deaconess Hospital  Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grethe \u00c5str\u00f8m","family":"Ueland","sequence":"additional","affiliation":[{"name":"Norwegian Diabetes Register for Adults, Norwegian Organization for Quality Improvement of Laboratory Examinations (Noklus) Haraldsplass Deaconess Hospital  Bergen Norway"},{"name":"Department of Internal Medicine Haukeland University Hospital  Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,4,25]]},"reference":[{"key":"e_1_2_12_2_1","unstructured":"L\u00f8vaasKF MadsenTV UelandG\u00c5 ErnesT SandbergS CooperJG.Norsk diabetesregister for voksne \u2010 data fra diabetespoliklinikker \u2013 \u00c5rsrapport 2020. 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