{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T04:23:29Z","timestamp":1782447809375,"version":"3.54.5"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T00:00:00Z","timestamp":1736553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabet Med"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Several wordings of the definition of severe hypoglycaemia (SH) exist. This study aims to evaluate how different SH definition wordings affect SH history assessment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this cross\u2010sectional study, surveys were emailed to registrants of the T1D Exchange, a U.S. national type 1 diabetes patient registry. Participants' demographic information was collected. Six\u2010month SH history was evaluated with questionnaires including SH definition wordings from either (1) professional societies, (2) a diabetes community website, or (3) a hypoglycaemia research questionnaire. Analyses included the McNemar test, pairwise Wilcoxon signed\u2010rank test, logistic regression analysis, Kappa statistics, and Spearman correlation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 1580 valid responses were obtained from participants (52% female; mean\u2009\u00b1\u2009SD age: 46\u2009\u00b1\u200915\u2009years; 95% White; mean\u2009\u00b1\u2009SD diabetes duration: 25\u2009\u00b1\u200916\u2009years). Questionnaires with four different SH definition wordings yielded significant variations in the prevalence of SH (i.e., having developed at least one episode of SH) and the number of SH episodes: the ADA\/ENDO 2013 definition wording yielded the highest results on both metrics, whereas HypoA\u2010Q and ADA 2023 yielded the lowest. Among participants reporting at least one SH episode, the number of episodes identified with the different SH definition wordings was poorly correlated (R<jats:sub>s<\/jats:sub>: 0.09\u20130.37; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Race, education level, and household income were associated with higher odds of discrepancies in SH history (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This U.S. national survey with individuals living with type 1 diabetes demonstrated significant discrepancies in SH history when assessed with different SH definition wordings. Race and socioeconomic status were associated with these discrepancies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dme.15513","type":"journal-article","created":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T08:59:52Z","timestamp":1736585992000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Evaluating the impact of severe hypoglycaemia definition wording on severe hypoglycaemia history assessment"],"prefix":"10.1111","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1988-7046","authenticated-orcid":false,"given":"Yu Kuei","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Internal Medicine University of Michigan  Ann Arbor USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Ye","sequence":"additional","affiliation":[{"name":"Department of Biostatistics University of Michigan  Ann Arbor USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Hepworth","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Michigan  Ann Arbor USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn","family":"Ang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Michigan  Ann Arbor USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2686-5531","authenticated-orcid":false,"given":"Stephanie A.","family":"Amiel","sequence":"additional","affiliation":[{"name":"Department of Diabetes Kings College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon J.","family":"Fisher","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Kentucky  Lexington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,11]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc17-1624"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc12-2480"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc18-S006"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.2337\/cd20-as01"},{"key":"e_1_2_10_6_1","first-page":"S111","article-title":"Glycemic goals and hypoglycemia: standards of Care in Diabetes\u20142024","volume":"47","author":"Committee ADAPP","year":"2023","journal-title":"Diabetes Care"},{"key":"e_1_2_10_7_1","unstructured":"Diabetes.co.uk.Severe Hypoglycemia. 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