{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T04:16:45Z","timestamp":1777954605685,"version":"3.51.4"},"reference-count":25,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabet Med"],"abstract":"Abstract<\/jats:title>\n \n Aim<\/jats:title>\n To characterise CGM\u2010derived glycaemic trajectories over 12months in people receiving maintenance haemodialysis, with a particular focus on hypoglycaemia burden and composite glycaemic risk.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n We conducted a longitudinal observational study. CGM data were collected at baseline, 6 and 12\u2009months. Descriptive statistics summarised characteristics. Outcomes included time in range (TIR), time below range (TBR), time above range (TAR), glycaemic variability (GV), hypoglycaemia burden and glycaemic risk index (GRI). Metrics were summarised using means or medians, and changes between timepoints were assessed using paired\n t<\/jats:italic>\n \u2010tests or Wilcoxon signed\u2010rank tests.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n In 125 participants (mean age 63.7\u2009years; 54.5% men), TIR increased from 51.6% at baseline to 56.6% at 6\u2009months (mean difference 5.09%, 95% CI 1.06 to 9.12;\n p<\/jats:italic>\n \u2009=\u20090.014) but was not sustained at 12\u2009months (50.5%;\n p<\/jats:italic>\n \u2009=\u20090.568), with a decline between 6 and 12\u2009months (\u22126.11%, 95% CI \u22129.03 to \u22123.19;\n p<\/jats:italic>\n \u2009<\u20090.001). TBR remained low, with a small increase between 6 and 12\u2009months (1.61%, 95% CI 0.59\u20132.64;\n p<\/jats:italic>\n \u2009=\u20090.002). TAR and GV were unchanged across timepoints. Hypoglycaemia burden increased over follow\u2010up (\n p<\/jats:italic>\n \u2009<\u20090.001), while GRI showed no change. HbA1c showed moderate concordance with CGM\u2010derived glucose at baseline (\n \u03c1<\/jats:italic>\n \u2009=\u20090.39;\n p<\/jats:italic>\n \u2009=\u20090.0001) and 12\u2009months (\n \u03c1<\/jats:italic>\n \u2009=\u20090.59;\n p<\/jats:italic>\n \u2009<\u20090.0001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n CGM revealed evolving glycaemic patterns. Early improvements in TIR were not sustained, hypoglycaemia increased modestly and the overall GRI remained unchanged. These findings support CGM\u2010informed, individualised diabetes management, prioritising safety and stability.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/dme.70344","type":"journal-article","created":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:14:16Z","timestamp":1777922056000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Unravelling dialysis\u2010related dysglycaemia: Longitudinal insights from continuous glucose monitoring"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8141-1423","authenticated-orcid":false,"given":"Hellena Hailu","family":"Habte\u2010Asres","sequence":"first","affiliation":[{"name":"Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care King's College London London UK"},{"name":"Royal Free London NHS Foundation Trust London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayodele","family":"Agbabiaka","sequence":"additional","affiliation":[{"name":"Royal Free London NHS Foundation Trust London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roha","family":"Rehan","sequence":"additional","affiliation":[{"name":"Royal Free London NHS Foundation Trust London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0745-3478","authenticated-orcid":false,"given":"David C.","family":"Wheeler","sequence":"additional","affiliation":[{"name":"UCL Department of Nephrology University College London, Royal Free Campus London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miranda","family":"Rosenthal","sequence":"additional","affiliation":[{"name":"King's College Hospital London 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with advanced CKD","volume":"42","author":"Habte\u2010Asres HH","year":"2024","journal-title":"Diabet Med"},{"issue":"6","key":"e_1_2_9_16_1","doi-asserted-by":"crossref","DOI":"10.3390\/diabetology6060049","article-title":"Glycemia risk index: a new metric to rule them all?","volume":"6","author":"Diaz Soto G","year":"2025","journal-title":"Diabetology"},{"issue":"3","key":"e_1_2_9_17_1","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.diabres.2015.01.026","article-title":"Effectiveness of continuous glucose monitoring in dialysis patients with diabetes: the DIALYDIAB pilot study","volume":"107","author":"Joubert M","year":"2015","journal-title":"Diabetes Res Clin Pract"},{"issue":"4","key":"e_1_2_9_18_1","doi-asserted-by":"crossref","first-page":"240","DOI":"10.5414\/CN108280","article-title":"Continuous glucose monitoring in hemodialyzed patients with type 2 diabetes: a multicenter pilot study","volume":"82","author":"K\u00e9p\u00e9n\u00e9kian 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