{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T14:10:24Z","timestamp":1792073424416,"version":"4.4.0"},"reference-count":32,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:00Z","timestamp":1782172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:00Z","timestamp":1782172800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100015769","name":"Dexcom","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015769","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabet Med"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>The type 1 diabetes population is ageing. Frailty is the age\u2010related physiological decline that occurs across organ systems, increasing the body's vulnerability to stressors. Current consensus\u2010based guidelines, derived from evidence in type 2 diabetes, prioritise hypoglycaemia avoidance, which increases falls, hospitalisation and mortality risk in older adults. This study assesses whether frailty is associated with increased hypoglycaemia in older adults with type 1 diabetes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Participants were over 65, with type 1 diabetes, confirmed by C\u2010peptide measurement. Frailty was categorized as robust, prefrail or frail as per Fried Frailty Phenotype (gait speed, weight loss, hand\u2010grip strength, exhaustion and physical activity). Secondary analyses used Clinical Frailty Scale and Short Physical Performance Battery. Cognition was assessed using Montreal Cognitive Assessment score (MoCA). Blinded continuous glucose monitors (CGM), Dexcom G6\/G7, were worn for 10\u2009days. CGM metrics were compared between frailty categories, focusing on percentage time below range (%TBR).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      83 participants met the inclusion criteria. 38 were robust (45.8%), 29 prefrail (34.9%) and 16 frail (19.3%). Frail participants were older, with more comorbidities and diabetes complications. Frailty was associated with higher HbA1c (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.025) and lower MoCA scores (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009&lt;\u20090.001). There was no difference between any CGM\u2010derived glycaemic parameter across the frailty spectrum, regardless of frailty assessment used.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>While frailty is often associated with hypoglycaemia in diabetes, this was not demonstrated in our type 1 diabetes cohort. Raised HbA1c levels with frailty may reflect recommendations to relax glucose targets. However, no difference was found in %TBR with frailty.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dme.70406","type":"journal-article","created":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T06:21:11Z","timestamp":1782282071000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The impact of frailty on glycaemic control in older adults with type 1 diabetes: An observational study"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2541-2848","authenticated-orcid":false,"given":"Jonathan A.","family":"Golding","sequence":"first","affiliation":[{"name":"University Hospitals Sussex NHS Foundation Trust  Brighton UK"},{"name":"Brighton and Sussex Medical School  Brighton UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scarlett O.","family":"Long","sequence":"additional","affiliation":[{"name":"Royal Devon University Healthcare NHS Trust  Exeter 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