{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T09:50:05Z","timestamp":1791625805023,"version":"4.3.4"},"reference-count":36,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T00:00:00Z","timestamp":1791590400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T00:00:00Z","timestamp":1791590400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabet Med"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>\n                      Previous reports have suggested that higher baseline BMI (bBMI) or %excess weight loss (EWL) are independent predictors of type 2 diabetes mellitus (T2DM) remission after metabolic bariatric surgery (MBS). However, %EWL appears lower in individuals with bBMI \u226550\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      than those with lower bBMI. Thus, this cohort study aimed to examine T2DM remission after MBS in adults with bBMI &lt;50\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      versus bBMI \u226550\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cohort study included adults with obesity and T2DM who underwent MBS between 01\/06\/2018 and 31\/05\/2024 at an Australian tertiary hospital. The primary outcome was complete diabetes remission (HbA1c\u2009&lt;\u20096.0%) at 12\u2009months following MBS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At 12\u2009months following MBS, when compared to those with bBMI &lt;50\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      , a higher proportion of patients with bBMI \u226550\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      experienced complete diabetes remission (37.8% vs. 66.7%, 95% CI for the difference \u221248.5% to \u22126.3%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.014); this was no longer significant after adjustment for variables such as baseline T2DM duration and HbA1c. The bBMI \u226550\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      group had greater total weight loss (kg) but lower %EWL, though neither was an independent predictor of remission.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      In our cohort, neither bBMI \u226550\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      nor %EWL appeared as an independent predictor of T2DM remission. The higher proportion with remission (on unadjusted analyses) in those with bBMI \u226550\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      potentially reflects less advanced diabetes despite greater obesity. Early consideration of MBS may be beneficial given that markers of diabetes duration\/severity appeared as potentially important variables associated with T2DM remission.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dme.70453","type":"journal-article","created":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T09:16:14Z","timestamp":1791623774000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Type 2 diabetes remission following a comprehensive metabolic program including surgery in adults with\n                    <scp>BMI<\/scp>\n                    \u226550\u2009kg\/m\n                    <sup>2<\/sup>\n                    versus\n                    <scp>BMI<\/scp>\n                    &lt;50\u2009kg\/m\n                    <sup>2<\/sup>"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8333-4502","authenticated-orcid":false,"given":"Xi 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