{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T05:44:25Z","timestamp":1791870265724,"version":"4.3.4"},"reference-count":64,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:00:00Z","timestamp":1791763200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:00:00Z","timestamp":1791763200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP2016801"],"award-info":[{"award-number":["APP2016801"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabet Med"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The increased risk of developing type 2 diabetes mellitus (T2DM) in the decade following childbirth among women with gestational diabetes mellitus (GDM) warrants early intervention. A prespecified update of a systematic review and meta\u2010analyses published in 2024 was performed, examining the efficacy of interventions to prevent T2DM among women within 5\u2009years of a GDM\u2010affected pregnancy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An updated search on PubMed, EMBASE and Web of Science (PROSPERO: CRD4202127989) was conducted on 14 November 2024. The primary outcome was T2DM diagnosis or measures of dysglycaemia with at least 12\u2009months follow\u2010up in women within 5\u2009years of a GDM\u2010complicated pregnancy. A Bayesian approach was adopted with results reported as effect sizes with 95% credible intervals (95% Crl), and posterior probabilities of intervention effectiveness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Nine new publications were identified in this updated search, resulting in a total of 26 publications from 25 studies (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20097379) included. Of those, four studies involved a pharmacological intervention and 21 evaluated lifestyle interventions. There was a 15% (95% CrI: 0.69\u20131.04) and 32% (95% CrI: 0.40\u20131.07) reduction in risk and hazard ratio for T2DM, respectively, with high posterior probabilities (95.0% and 96.0%, respectively). Reductions were observed for other secondary metabolic outcomes (fasting plasma glucose, body mass index, HOMA\u2010IR and total cholesterol).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Compared to the original review, this update indicates greater certainty of the efficacy of preventive interventions for T2DM in women delivered during the first 5\u2009years after a GDM\u2010affected pregnancy. Evidence on the efficacy and safety of pharmacotherapy interventions is still limited.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dme.70486","type":"journal-article","created":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T04:45:27Z","timestamp":1791866727000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The efficacy of interventions to prevent type 2 diabetes among women with recent gestational diabetes mellitus\u2014First update of a living systematic review and meta\u2010analysis"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9118-9835","authenticated-orcid":false,"given":"Vivian Y. 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