{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:43:35Z","timestamp":1790837015174,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2015,10,8]],"date-time":"2015-10-08T00:00:00Z","timestamp":1444262400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001648","name":"European Foundation for the Study of Diabetes","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001648","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004719","name":"LifeScan, Inc.","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004719","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>\n                      To validate strategies to prevent exercise\u2010induced hypoglycaemia via insulin\u2010dose adjustment in adult patients with type 1 diabetes (\n                      <jats:styled-content style=\"fixed-case\">T1D<\/jats:styled-content>\n                      ) on pump therapy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A total of 20 patients randomly performed four 30\u2010min late post\u2010lunch (3 h after lunch) exercise sessions and a rest session: two moderate sessions [50% maximum oxygen consumption (\n                      <jats:styled-content style=\"fixed-case\">\n                        VO\n                        <jats:sub>2<\/jats:sub>\n                        max\n                      <\/jats:styled-content>\n                      )] with 50 or 80% basal rate (\n                      <jats:styled-content style=\"fixed-case\">BR<\/jats:styled-content>\n                      ) reduction during exercise + 2 h and two intense sessions (75%\n                      <jats:styled-content style=\"fixed-case\">\n                        VO\n                        <jats:sub>2<\/jats:sub>\n                        max\n                      <\/jats:styled-content>\n                      ) with 80%\n                      <jats:styled-content style=\"fixed-case\">BR<\/jats:styled-content>\n                      reduction or with their pump stopped. Two additional early post\u2010lunch sessions (90 min after lunch) were analysed to compare hypoglycaemia incidence for\n                      <jats:styled-content style=\"fixed-case\">BR<\/jats:styled-content>\n                      reduction versus bolus reduction.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In all, 100 late post\u2010lunch sessions were analysed. Regardless of exercise type and\n                      <jats:styled-content style=\"fixed-case\">BR<\/jats:styled-content>\n                      reduction, no more hypoglycaemic events occurred in the period until the next morning than occurred after the rest sessions. In the afternoon, no more hypoglycaemic events occurred with 80%\n                      <jats:styled-content style=\"fixed-case\">BR<\/jats:styled-content>\n                      reduction\/moderate exercise or with pump discontinuation\/intense exercise than for the rest session, whereas more hypoglycaemic events occurred with 50%\n                      <jats:styled-content style=\"fixed-case\">BR<\/jats:styled-content>\n                      reduction\/moderate exercise and 80%\n                      <jats:styled-content style=\"fixed-case\">BR<\/jats:styled-content>\n                      reduction\/intense exercise. After early post\u2010lunch exercise (n = 37), a trend towards fewer hypoglycaemic episodes was observed with bolus reduction versus\n                      <jats:styled-content style=\"fixed-case\">BR<\/jats:styled-content>\n                      reduction (p = 0.07). Mean blood glucose fell by \u223c3.3 mmol\/l after 30 min of exercise, irrespective of dose reduction, remaining stable until the next morning with no rebound hyperglycaemia.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      In adults with\n                      <jats:styled-content style=\"fixed-case\">T1D<\/jats:styled-content>\n                      , to limit the hypoglycaemic risk associated with 30 min of exercise 3 h after lunch, without carbohydrate supplements, the best options seem to be to reduce\n                      <jats:styled-content style=\"fixed-case\">BR<\/jats:styled-content>\n                      by 80% or to stop the pump for moderate or intense exercise, or for moderate exercise 90 min after lunch, to reduce the prandial bolus rather than the\n                      <jats:styled-content style=\"fixed-case\">BR<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.12552","type":"journal-article","created":{"date-parts":[[2015,8,12]],"date-time":"2015-08-12T02:55:37Z","timestamp":1439348137000},"page":"1150-1157","source":"Crossref","is-referenced-by-count":84,"title":["Insulin\u2010based strategies to prevent hypoglycaemia during and after exercise in adult patients with type 1 diabetes on pump therapy: the\n                    <scp>DIABRASPORT<\/scp>\n                    randomized study"],"prefix":"10.1111","volume":"17","author":[{"given":"S.","family":"Franc","sequence":"first","affiliation":[{"name":"Centre for Study and Research for Improvement of the Treatment of Diabetes (CERITD)  Evry France"},{"name":"Department of Diabetes Sud\u2010Francilien Hospital  Corbeil\u2010Essonnes 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