{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T12:09:50Z","timestamp":1787659790584,"version":"build-2736575974"},"reference-count":33,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,7,27]],"date-time":"2017-07-27T00:00:00Z","timestamp":1501113600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"JSPS KAKENHI","award":["26860701"],"award-info":[{"award-number":["26860701"]}]},{"DOI":"10.13039\/100012319","name":"National Center for Global Health and Medicine","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100012319","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>\n                      Diabetes\u2010related complications have declined during the past two decades. We aimed to examine whether mortality in people with diabetes improved over time in the 1999 to 2010\n                      <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>\n                      ational\n                      <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>\n                      ealth and\n                      <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>\n                      utrition\n                      <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>\n                      xamination\n                      <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>\n                      urvey (\n                      <jats:styled-content style=\"fixed-case\">NHANES<\/jats:styled-content>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We conducted a prospective cohort study using 1999 to 2004 and 2005 to 2010 data from the\n                      <jats:styled-content style=\"fixed-case\">NHANES<\/jats:styled-content>\n                      . For primary analyses, we compared the unadjusted, age\u2010adjusted and multivariable\u2010adjusted hazard ratios (\n                      <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\n                      ) for mortality outcomes (total, cardiovascular, cardiac and cancer deaths) of the participants with diabetes with those without diabetes using\n                      <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>\n                      ox proportional hazard models.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      For each mortality outcome,\n                      <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\n                      (95% confidence interval) in diabetic participants during the period 2005 to 2010 was lower than that during the period 1999 to 2004 (all\u2010cause death, 2.76 [1.87\u20104.08] vs 4.23 [2.57\u20106.98]; cardiovascular death, 2.70 [1.20\u20106.04] vs 8.82 [3.28\u201023.70]; cardiac death, 2.45 [0.98\u20106.09] vs 15.55 [7.01\u201034.50]; cancer death, 2.33 [0.87\u20106.23] vs 3.03 [1.20\u20107.65]). Compared with mortality outcome during the period 1999 to 2004, greater declines in mortality during the period 2005 to 2010 were observed for cardiovascular (\u221254.0%) and cardiac deaths (\u221264.8%). In age\u2010adjusted and multivariable\u2010adjusted models, the cumulative event rates for total, cardiovascular and cardiac deaths were not significantly different between participants with and without diabetes during the period 2005\u20132010; this was not the case during the period 1999\u20132004. The leading cause of death was malignant neoplasm during the period 2005\u20132010.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Considerably improved outcomes for total, cardiovascular and cardiac deaths were observed in people with diabetes during the 2005 to 2010\n                      <jats:styled-content style=\"fixed-case\">NHANES<\/jats:styled-content>\n                      compared to the 1999 to 2004\n                      <jats:styled-content style=\"fixed-case\">NHANES<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.13039","type":"journal-article","created":{"date-parts":[[2017,6,22]],"date-time":"2017-06-22T11:52:34Z","timestamp":1498132354000},"page":"85-93","source":"Crossref","is-referenced-by-count":19,"title":["Favourable changes in mortality in people with diabetes:\n                    <scp>US NHANES<\/scp>\n                    1999\u20132010"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0230-1718","authenticated-orcid":false,"given":"Tetsuro","family":"Tsujimoto","sequence":"first","affiliation":[{"name":"Department of Diabetes, Endocrinology, and Metabolism Center Hospital, National Center for Global Health and Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Kajio","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Endocrinology, and Metabolism Center Hospital, National Center for Global Health and Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takehiro","family":"Sugiyama","sequence":"additional","affiliation":[{"name":"Department of Clinical Study and Informatics, Center for Clinical Sciences National Center for Global Health and Medicine  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