{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T11:32:23Z","timestamp":1792150343974,"version":"4.4.0"},"reference-count":49,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,7,16]],"date-time":"2018-07-16T00:00:00Z","timestamp":1531699200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007687","name":"Korean Diabetes Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007687","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To compare pancreatic volume and fat amount, and their associations with glucose homeostasis, in a Korean and a white population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>\n                      In 43 healthy Korean and 43 healthy white people, matched for age (\u00b13 years) and body mass index (BMI; \u00b11 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ), we measured pancreatic volume and fat amount in the pancreas and abdomen using computed tomography. Pancreatic \u03b2\u2010cell function and insulin resistance were estimated according to biochemical characteristics and a 75\u2010g oral glucose tolerance test. Body composition and resting energy expenditure (REE) were examined using bioimpedance and indirect calorimetry, respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The mean\u2009\u00b1SD age of the participants was 29.9\u2009\u00b1\u20095.9 years and 30.0\u2009\u00b1\u20095.2 years, and BMI was 24.0\u2009\u00b13.7 and 24.1\u2009\u00b13.2 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      in the white participants and the Korean participants, respectively. Pancreatic volume in the white participants was greater than that in Korean participants (77.8\u2009\u00b111.6 vs 68.2\u2009\u00b112.1 cm\n                      <jats:sup>3<\/jats:sup>\n                      ;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.001). Pancreatic fat content in Korean participants was 22.8% higher than in white participants (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.051). Insulinogenic index, disposition index, muscle mass and REE were significantly lower in Korean participants. Pancreatic volume was positively associated with indices linked to \u03b2\u2010cell function; fat content in the pancreas was negatively associated with such indices, and positively with insulin resistance after adjusting for relevant variables including REE.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A smaller pancreas and higher fat deposition might be crucial determinants of vulnerability to diabetes in Korean people compared with white people with similar BMI and body fat levels.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.13447","type":"journal-article","created":{"date-parts":[[2018,6,23]],"date-time":"2018-06-23T00:54:52Z","timestamp":1529715292000},"page":"2642-2652","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Comparison of pancreatic volume and fat amount linked with glucose homeostasis between healthy Caucasians and Koreans"],"prefix":"10.1111","volume":"20","author":[{"given":"Eun","family":"Roh","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Seoul National University College of Medicine and Seoul National University Bundang Hospital  Seongnam South Korea"},{"name":"Department of Internal Medicine Korea University Guro Hospital  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoung M.","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Seoul National University College of Medicine and Seoul National University Bundang Hospital  Seongnam South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyeong S.","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Seoul National University College of Medicine and Seoul National University Bundang Hospital  Seongnam South Korea"},{"name":"Department of Internal Medicine Daerim Saint Mary's Hospital  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoon J.","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Seoul National University College of Medicine and Seoul National University Bundang Hospital  Seongnam South Korea"},{"name":"Department of Internal Medicine Mediplex Sejong Hospital  Incheon South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun J.","family":"Chun","sequence":"additional","affiliation":[{"name":"Department of Radiology Seoul National University College of Medicine and Seoul National University Bundang Hospital  Seongnam South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung H.","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Seoul National University College of Medicine and Seoul National University Bundang Hospital  Seongnam South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyong S.","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Seoul National University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hak C.","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Seoul National University College of Medicine and Seoul National University Bundang Hospital  Seongnam South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4137-1671","authenticated-orcid":false,"given":"Soo","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Seoul National University College of Medicine and Seoul National University Bundang Hospital  Seongnam South 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