{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T13:03:57Z","timestamp":1791464637951,"version":"4.3.4"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,2,14]],"date-time":"2019-02-14T00:00:00Z","timestamp":1550102400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100005485","name":"American College of Cardiology Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005485","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004873","name":"State of Massachusetts Department of Conservation and Recreation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004873","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001003","name":"Boehringer Ingelheim","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001003","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To investigate multiple risk factor target attainment in adults with diabetes mellitus (DM) for atherosclerotic cardiovascular disease (ASCVD) prevention and the predictors of such attainment in a contemporary DM registry.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In the US Diabetes Collaborative Registry we identified patients who were at target for glycated haemoglobin (HbA1c; &lt; 53 mmol\/mol (7%) or &lt; 64 mmol\/mol (8%) if with ASCVD), LDL cholesterol (&lt; 2.6 mmol\/L (100 mg\/dL) or &lt; 1.8 mmol\/L (70 mg\/dL) 1.8 if with ASCVD) and blood pressure (BP; &lt;140\/90\u2009mmHg and &lt;\u2009130\/80\u2009mmHg as an alternate), and who had non\u2010smoking status, by sex, race and history of ASCVD. Multiple logistic regression was used to examine predictors of target attainment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In 74\u2009393 patients with DM who had available data (mean age 69.0 years, 41.0% women), overall target attainment for HbA1c, BP, LDL cholesterol and non\u2010smoking status was 73.6%, 69.0% (40.3% for BP &lt;130\/80\u2009mmHg), 48.6% and 85.2%, respectively. Only 21.6% (13.0% with BP &lt;130\/80\u2009mmHg) were at target for all four measures, and the proportions were higher in men (23.6%) versus women (18.6%) and in white people (22.5%) versus African\u2010American people (14.7%) and people of other races (20.8%;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.01). A total of 62.4% were on a moderate\u2010\/high\u2010intensity statin. Age (\u226565\u2009years: odds ratio [OR] 1.9, 95% confidence interval [CI] 1.7\u20102.0; and 55\u201064\u2009years: OR 1.3, 95% CI 1.2\u20101.4 vs. &lt;55\u2009years), male sex (OR 1.3, 95% CI 1.3\u20101.4), white race (OR 1.4, 95% CI 1.3\u20101.5), middle or high income (ORs 1.1, 95% CI 1.1\u20101.2 or 1.4, 95% CI 1.4\u20101.5, respectively) were associated, and depression (OR 0.9, 95% CI 0.8\u20101.0) was inversely associated with meeting all four targets (all\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.01 to\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In our US registry of patients with DM, only one in five patients were achieving comprehensive risk factor control. Multifactorial interventions will be necessary to optimize ASCVD risk factor control.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.13625","type":"journal-article","created":{"date-parts":[[2019,1,4]],"date-time":"2019-01-04T13:46:22Z","timestamp":1546609582000},"page":"1121-1127","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":52,"title":["Composite cardiovascular risk factor target achievement and its predictors in US adults with diabetes: The Diabetes Collaborative Registry"],"prefix":"10.1111","volume":"21","author":[{"given":"Wenjun","family":"Fan","sequence":"first","affiliation":[{"name":"University of California, Irvine School of Medicine  Irvine California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Song","sequence":"additional","affiliation":[{"name":"Baim Institute  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvio E.","family":"Inzucchi","sequence":"additional","affiliation":[{"name":"Yale School of Medicine  New Haven Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence","family":"Sperling","sequence":"additional","affiliation":[{"name":"Emory University  Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher P.","family":"Cannon","sequence":"additional","affiliation":[{"name":"Baim Institute  Boston Massachusetts"},{"name":"Harvard Medical School  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanne V.","family":"Arnold","sequence":"additional","affiliation":[{"name":"St. Lukes Health System  Kansas City Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3750-9789","authenticated-orcid":false,"given":"Mikhail","family":"Kosiborod","sequence":"additional","affiliation":[{"name":"St. Lukes Health System  Kansas City Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1102-7324","authenticated-orcid":false,"given":"Nathan D.","family":"Wong","sequence":"additional","affiliation":[{"name":"University of California, Irvine School of Medicine  Irvine California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,2,14]]},"reference":[{"issue":"1","key":"e_1_2_8_2_1","doi-asserted-by":"crossref","first-page":"S60","DOI":"10.2337\/dc16-S011","article-title":"Cardiovascular disease and risk management. 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