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Patients with AD had a mean Eczema Area and Severity Index score of 8.5\u2009\u00b1\u20091.0 (moderate disease) and a mean AD duration of 28\u2009\u00b1\u20093\u2009years. During the OGTT, circulating glucose, insulin, C\u2010peptide, glucagon and glucose\u2010dependent insulinotropic polypeptide, respectively, were similar in the two groups, except glucagon\u2010like peptide\u20101, which was higher in patients with AD. The clamp showed no differences in insulin sensitivity between groups (M\u2010value 9.2\u2009\u00b1\u20090.6 vs. 9.8\u2009\u00b1\u20090.8,\n                      <jats:italic>P<\/jats:italic>\n                      = .541, 95% CI \u22121.51; 2.60), or circulating insulin, C\u2010peptide and glucagon levels.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Using OGTT and the hyperinsulinaemic euglycaemic clamp technique, we found no difference in insulin sensitivity or other gluco\u2010metabolic characteristics between patients with mild to moderate AD and matched healthy controls, suggesting that the inflammatory skin disease AD has little or no influence on glucose metabolism.<\/jats:p>\n                  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