{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:48:16Z","timestamp":1787014096606,"version":"build-2736575974"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,11,17]],"date-time":"2020-11-17T00:00:00Z","timestamp":1605571200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Basal insulin is often prescribed to patients with suboptimally controlled type 2 diabetes (T2D); however, its therapeutic efficacy is inadequate in many. During the MOBILE study's baseline phase, we evaluated 173 participants' continuous glucose monitoring (CGM) data (mean\u2009\u00b1\u2009SD age 57\u2009\u00b1\u20099\u2009years; 50% female; HbA1c 9.1% [range 7.1%\u201011.6%]; 40% using sulphonylureas; 19% using NPH; reported self\u2010monitored blood glucose [SMBG] frequency median 1.0 checks\/day) who were using basal, but not prandial insulin. Blinded CGM data were recorded for 10\u2009days prior to randomization. The mean glucose value was 208\u2009\u00b1\u200947\u2009mg\/dL and it was lowest in the early morning. Mean time in the 70\u2010180\u2009mg\/dL range was 9.6 \u00b1\u20096.1 hours\/day (40%\u2009\u00b1\u200925%). Hyperglycaemia was extensive with medians of 14.7 (61%) and 5.0 (20.9%) hours\/day with glucose greater than 180 and\u2009250\u2009mg\/dL, respectively. Hypoglycaemia was infrequent (median [IQR] 0 [0, 4.3] minutes\/day [0.0% {0.0%, 0.3%}] with glucose less than 70\u2009mg\/dL). Blinded CGM highlights the limitations of infrequent SMBG in basal insulin users with T2D and allows characterization of hyperglycaemia and hypoglycaemia in basal insulin users with suboptimal control. The MOBILE study randomized phase will define the benefits of using real\u2010time CGM compared with SMBG in this population.<\/jats:p>","DOI":"10.1111\/dom.14238","type":"journal-article","created":{"date-parts":[[2020,10,29]],"date-time":"2020-10-29T03:46:19Z","timestamp":1603943179000},"page":"631-636","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Glycaemic profiles of diverse patients with type 2 diabetes using basal insulin:\n                    <scp>MOBILE<\/scp>\n                    study baseline data"],"prefix":"10.1111","volume":"23","author":[{"given":"Anne","family":"Peters","sequence":"first","affiliation":[{"name":"Keck School of Medicine of the University of Southern California  Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan","family":"Cohen","sequence":"additional","affiliation":[{"name":"Jaeb Center for Health Research  Tampa Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5325-7200","authenticated-orcid":false,"given":"Peter","family":"Calhoun","sequence":"additional","affiliation":[{"name":"Jaeb Center for Health Research  Tampa Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrina J.","family":"Ruedy","sequence":"additional","affiliation":[{"name":"Jaeb Center for Health Research  Tampa Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy W.","family":"Beck","sequence":"additional","affiliation":[{"name":"Jaeb Center for Health Research  Tampa Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas W.","family":"Martens","sequence":"additional","affiliation":[{"name":"International Diabetes Center, Park Nicollet Clinic  Brooklyn Center Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shichun","family":"Bao","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center  Nashville Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelly M.","family":"Njeru","sequence":"additional","affiliation":[{"name":"Dexcom, Inc.  San Diego California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stayce E.","family":"Beck","sequence":"additional","affiliation":[{"name":"Dexcom, Inc.  San Diego California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Price","sequence":"additional","affiliation":[{"name":"Dexcom, Inc.  San Diego California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,11,17]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc16-1974"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.12626"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.13683"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/193229680700100412"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.12072"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.13607"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.13663"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1185\/03007995.2013.803053"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.13673"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.13064"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcd.2017.10.001"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.13946"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.13832"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/193229681100500320"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc11-1438"},{"key":"e_1_2_9_17_1","article-title":"Feasibility of a new approach to initiate insulin in type 2 diabetes","author":"Aradottir TB","year":"2020","journal-title":"J Diabetes Sci Technol."},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc16-1769"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.2337\/dci19-0028"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1185\/03007995.2011.621416"}],"container-title":["Diabetes, Obesity and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dom.14238","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/dom.14238","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dom-pubs.pericles-prod.literatumonline.com\/doi\/pdf\/10.1111\/dom.14238","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T06:57:03Z","timestamp":1761893823000},"score":1,"resource":{"primary":{"URL":"https:\/\/dom-pubs.pericles-prod.literatumonline.com\/doi\/10.1111\/dom.14238"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,17]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["10.1111\/dom.14238"],"URL":"https:\/\/doi.org\/10.1111\/dom.14238","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/DOM.14238\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.14238\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.14238\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.14238\/v1\/review4","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.14238\/v1\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.14238\/v1\/review5","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.14238\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.14238\/v2\/decision1","asserted-by":"object"}]},"ISSN":["1462-8902","1463-1326"],"issn-type":[{"value":"1462-8902","type":"print"},{"value":"1463-1326","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,17]]},"assertion":[{"value":"2020-08-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}