{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T20:37:19Z","timestamp":1780346239640,"version":"3.54.1"},"reference-count":44,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,12,2]],"date-time":"2020-12-02T00:00:00Z","timestamp":1606867200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To conduct a meta\u2010analysis to determine the effects of continuous positive airway pressure (CPAP) treatment on glycaemic control and insulin resistance in patients with type 2 diabetes and obstructive sleep apnoea (OSA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A systematic search was made of the MEDLINE, SCOPUS, ISI Web of Science, Cochrane databases, and\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">clinicaltrials.gov<\/jats:ext-link>\n                      , without language restrictions. Randomized controlled trials on treatment of type 2 diabetes and OSA with CPAP, compared with sham CPAP or no CPAP, were reviewed. Studies were pooled to obtain standardized mean differences (SMDs), with 95% confidence intervals (CIs).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Seven trials (enrolling 691 participants) met the inclusion criteria. CPAP showed significant effects on glycated haemoglobin (HbA1c; SMD \u22120.32, 95% CI \u22120.60 to \u22120.03;\n                      <jats:italic>P<\/jats:italic>\n                      = 0.029), fasting glucose (SMD \u22120.39, 95% CI \u22120.76 to \u22120.02;\n                      <jats:italic>P<\/jats:italic>\n                      = 0.040), homeostatic model assessment of insulin resistance (HOMA\u2010IR; SMD \u22121.05, 95% CI \u22121.91 to \u22120.19;\n                      <jats:italic>P<\/jats:italic>\n                      = 0.016), systolic blood pressure (SMD \u22121.18, 95% CI \u22122.29 to \u22120.07\u2009mm Hg;\n                      <jats:italic>P<\/jats:italic>\n                      = 0.037), and diastolic blood pressure (SMD \u22121.29, 95% CI \u22122.48 to \u22120.09;\n                      <jats:italic>P<\/jats:italic>\n                      = 0.035).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Continuous positive airway pressure treatment significantly improved glycaemic control and insulin resistance, as shown by the decreased HbA1c levels, fasting glucose levels and HOMA\u2010IR values in patients with type 2 diabetes and OSA.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.14247","type":"journal-article","created":{"date-parts":[[2020,11,4]],"date-time":"2020-11-04T12:48:38Z","timestamp":1604494118000},"page":"540-548","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["Benefits of continuous positive airway pressure on glycaemic control and insulin resistance in patients with type 2 diabetes and obstructive sleep apnoea: A meta\u2010analysis"],"prefix":"10.1111","volume":"23","author":[{"given":"Wenli","family":"Shang","sequence":"first","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine Shaanxi 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