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Currently, weight loss is the most effective treatment for NAFLD (even in the minority of patients with NAFLD who do not have obesity) and is recommended in all national and international guidelines. Accumulating evidence has shown that weight loss, whether achieved by diet and lifestyle interventions, bariatric surgery or pharmacotherapy, can improve biomarkers of NAFLD, as well as prevent progression and, in some cases, reverse fibrosis. There is a dose dependency of weight loss with NAFLD improvement. Pharmacotherapy with antiobesity medications, alone or in combination with intensive lifestyle interventions or other weight\u2010loss drugs, is closing the efficacy gap between diet and exercise and weight\u2010loss surgery in efficacy at reversing obesity. Given the importance of providing effective weight\u2010loss treatment to patients with NAFLD, weight management services need to be made increasingly available and embedded within hepatology services. 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