{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T22:07:37Z","timestamp":1793225257590,"version":"4.5.0"},"reference-count":154,"publisher":"Wiley","issue":"S3","license":[{"start":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T00:00:00Z","timestamp":1685404800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We reviewed recent guidelines on the management of heart failure (HF) in patients with diabetes. Major recommendations in European and US society guidelines were scrutinized. First, sodium\u2010glucose co\u2010transporter 2 inhibitors are now recommended treatments for all patients with symptomatic HF (stage C and D; New York Heart Association class II\u2010IV), irrespective of the presence of type 2 diabetes and left ventricular ejection fraction (LVEF). Second, patients with HF and reduced EF (LVEF \u226440%) should have foundational therapies from four drug classes (sodium\u2010glucose co\u2010transporter 2 inhibitor, angiotensin\u2010receptor neprilysin inhibitor, beta\u2010blocker and mineralocorticoid receptor antagonist). Third, patients with HF with mildly reduced (41%\u201049%) and preserved (\u226550%) LVEF may also benefit from angiotensin\u2010receptor neprilysin inhibitor, beta\u2010blocker and mineralocorticoid receptor antagonist therapy, although evidence for these is less robust. Fourth, selected patients should be considered for other therapies such as diuretics (if congestion), anticoagulation (if atrial fibrillation) and cardiac device therapy. Fifth, glucose\u2010lowering therapies such as thiazolidinediones and certain dipeptidyl peptidase\u20104 inhibitors (such as saxagliptin and alogliptin) should be avoided in patients with HF. Sixth, guidelines recommend enrolment of patients with HF into exercise rehabilitation and multidisciplinary HF management programmes. Particular attention should be paid to important comorbidities such as obesity, alongside pharmacological therapies. As diabetes and obesity are major risk factors for HF, earlier consideration of, and diagnosis of HF, followed by guideline\u2010directed medical therapy can meaningfully improve patients' lives. Diabetes doctors would do well to understand the basics of such guidelines to help improve all aspects of HF diagnosis and care.<\/jats:p>","DOI":"10.1111\/dom.15085","type":"journal-article","created":{"date-parts":[[2023,4,11]],"date-time":"2023-04-11T23:46:17Z","timestamp":1681256777000},"page":"33-47","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["A review of current key guidelines for managing high\u2010risk patients with diabetes and heart failure and future prospects"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9213-2067","authenticated-orcid":false,"given":"Matthew M. Y.","family":"Lee","sequence":"first","affiliation":[{"name":"School of Cardiovascular and Metabolic Health, BHF Glasgow Cardiovascular Research Centre University of Glasgow  Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1604-2593","authenticated-orcid":false,"given":"Naveed","family":"Sattar","sequence":"additional","affiliation":[{"name":"School of Cardiovascular and Metabolic Health, BHF Glasgow Cardiovascular Research Centre University of Glasgow  Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,30]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213\u20108587(22)00249\u20102"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehab368"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000001040"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000001063"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.2337\/dci22\u20100014"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125\u2010022\u201005787\u20102"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehz486"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.1673"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1911303"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2206286"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2022190"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2107038"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2030183"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2020.7585"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.120.051783"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.2420"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2022.3750"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.1906"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.120.051824"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.122.059785"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213\u20108587(22)00308\u20104"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.120.050391"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.120.051685"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2022.2924"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2022.4210"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.119.044138"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa1007"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.121.057812"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2022.11.006"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aace.2020.11.009"},{"key":"e_1_2_12_32_1","unstructured":"emc. Jardiance (empagliflozin). Published. 2022. Accessed January 3 2023.https:\/\/www.medicines.org.uk\/emc\/product\/5441\/"},{"key":"e_1_2_12_33_1","unstructured":"emc. Forxiga (dapagliflozin). Published.2022. Accessed January 3 2023https:\/\/www.medicines.org.uk\/emc\/product\/7607\/"},{"key":"e_1_2_12_34_1","unstructured":"Janssen. Invokana (canagliflozin). Published.2022. Accessed January 3 2023https:\/\/www.janssenlabels.com\/package-insert\/product-monograph\/prescribing-information\/INVOKANA-pi.pdf"},{"key":"e_1_2_12_35_1","unstructured":"Merck. Steglatro (ertugliflozin). Published. 2022. Accessed January 3 2023https:\/\/www.merck.com\/product\/usa\/pi_circulars\/s\/steglatro\/steglatro_pi.pdf"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.122.061732"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.120.052926"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.04.025"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.11.022"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572\u2010020\u20100151\u20107"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.08.001"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(22)02076\u20101"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591\u2010021\u201001659\u20101"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198706043162301"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1995.03520420066040"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.100.23.2312"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199108013250501"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1409077"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.115.002560"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213\u20108587(17)30087\u20106"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)04440-2"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199605233342101"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200105313442201"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.283.10.1295"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000035653.72855.bf"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi115"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)11181-9"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0002\u20109149(97)00849\u20107"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.05.011"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.1054\/jcaf.2003.31"},{"key":"e_1_2_12_61_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199909023411001"},{"key":"e_1_2_12_62_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1009492"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.117.006540"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.117.008054"},{"key":"e_1_2_12_65_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1908655"},{"key":"e_1_2_12_66_1","unstructured":"Novartis. Novartis Entresto\u00ae granted expanded indication in chronic heart failure by FDA. Published.2021. Accessed January 3 2023https:\/\/www.novartis.com\/news\/media-releases\/novartis-entresto-granted-expanded-indication-chronic-heart-failure-fda"},{"key":"e_1_2_12_67_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv464"},{"key":"e_1_2_12_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchf.2019.09.009"},{"key":"e_1_2_12_69_1","unstructured":"Bayer. A multicenter randomized double\u2010blind parallel\u2010group placebo\u2010controlled study to evaluate the efficacy and safety of Finerenone on morbidity and mortality in participants with heart failure (NYHA II\u2010IV) and left ventricular ejection fraction \u2265 40% (LVEF \u2265 40%). ClinicalTrials.gov. Published 2020. Accessed December 25 2022https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04435626"},{"key":"e_1_2_12_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdiacomp.2019.05.001"},{"key":"e_1_2_12_71_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.1402"},{"key":"e_1_2_12_72_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa612"},{"key":"e_1_2_12_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2011.09.030"},{"key":"e_1_2_12_74_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0905561"},{"key":"e_1_2_12_75_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1009638"},{"key":"e_1_2_12_76_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1107039"},{"key":"e_1_2_12_77_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1310907"},{"key":"e_1_2_12_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(10)61198\u20101"},{"key":"e_1_2_12_79_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.347"},{"key":"e_1_2_12_80_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa042934"},{"key":"e_1_2_12_81_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1915928"},{"key":"e_1_2_12_82_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0908355"},{"key":"e_1_2_12_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(20)32339\u20104"},{"key":"e_1_2_12_84_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.092973"},{"key":"e_1_2_12_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.08.007"},{"key":"e_1_2_12_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.08.009"},{"key":"e_1_2_12_87_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1602001"},{"key":"e_1_2_12_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.07.047"},{"key":"e_1_2_12_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2014.07.007"},{"key":"e_1_2_12_90_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezaa319"},{"key":"e_1_2_12_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.11.001"},{"key":"e_1_2_12_92_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.116.004132"},{"key":"e_1_2_12_93_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.110.959510"},{"key":"e_1_2_12_94_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1009540"},{"key":"e_1_2_12_95_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc22\u2010Sint"},{"key":"e_1_2_12_96_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc08\u20109026"},{"key":"e_1_2_12_97_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125\u2010012\u20102681\u20103"},{"key":"e_1_2_12_98_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000691"},{"key":"e_1_2_12_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2011.07.030"},{"key":"e_1_2_12_100_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.023518"},{"key":"e_1_2_12_101_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc21\u2010S010"},{"key":"e_1_2_12_102_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.1170"},{"key":"e_1_2_12_103_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.112.000162"},{"key":"e_1_2_12_104_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.116.005379"},{"key":"e_1_2_12_105_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125\u2010010\u20101906\u20106"},{"key":"e_1_2_12_106_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.14533"},{"key":"e_1_2_12_107_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.019211"},{"key":"e_1_2_12_108_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b4731"},{"key":"e_1_2_12_109_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1307684"},{"key":"e_1_2_12_110_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000330"},{"key":"e_1_2_12_111_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1305889"},{"key":"e_1_2_12_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(14)62225\u2010X"},{"key":"e_1_2_12_113_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12933\u2010017\u20100593\u20108"},{"key":"e_1_2_12_114_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2016.0103"},{"key":"e_1_2_12_115_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.118.038352"},{"key":"e_1_2_12_116_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1501352"},{"key":"e_1_2_12_117_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.18269"},{"key":"e_1_2_12_118_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchf.2017.08.004"},{"key":"e_1_2_12_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2019.02.014"},{"key":"e_1_2_12_120_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.06.208"},{"key":"e_1_2_12_121_1","doi-asserted-by":"publisher","DOI":"10.9778\/cmajo.20160058"},{"key":"e_1_2_12_122_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa072761"},{"key":"e_1_2_12_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(07)61514\u20101"},{"key":"e_1_2_12_124_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.1.256"},{"key":"e_1_2_12_125_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(09)60953\u20103"},{"key":"e_1_2_12_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(05)67528\u20109"},{"key":"e_1_2_12_127_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2019.0079"},{"key":"e_1_2_12_128_1","doi-asserted-by":"publisher","DOI":"10.1177\/1479164118825376"},{"key":"e_1_2_12_129_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.117.030924"},{"key":"e_1_2_12_130_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1615692"},{"key":"e_1_2_12_131_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.1146"},{"key":"e_1_2_12_132_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.1535"},{"key":"e_1_2_12_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(18)32261\u2010X"},{"key":"e_1_2_12_134_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2108269"},{"key":"e_1_2_12_135_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.657"},{"key":"e_1_2_12_136_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.10260"},{"key":"e_1_2_12_137_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.14862"},{"key":"e_1_2_12_138_1","unstructured":"Novo Nordisk A\/S.Research study to look at how well semaglutide works in people living with heart failure obesity and type 2 diabetes (STEP HFpEF DM). ClinicalTrials.gov. Published2021. Accessed December 25 2022https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04916470"},{"key":"e_1_2_12_139_1","unstructured":"Novo Nordisk A\/S.Research study to investigate how well Semaglutide works in people living with heart failure and obesity (STEP\u2010HFpEF). ClinicalTrials.gov. Published2021. Accessed December 25 2022https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04788511"},{"key":"e_1_2_12_140_1","unstructured":"EliLilly and Company.A study of tirzepatide (LY3298176) in participants with heart failure with preserved ejection fraction and obesity (SUMMIT). ClinicalTrials.gov Published2021. Accessed December 25 2022https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04847557"},{"key":"e_1_2_12_141_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2017.08.022"},{"issue":"1","key":"e_1_2_12_142_1","first-page":"196","article-title":"A WHO report: framework for action on interprofessional education and collaborative practice","volume":"39","author":"Gilbert JHV","year":"2010","journal-title":"J Allied Health"},{"key":"e_1_2_12_143_1","doi-asserted-by":"publisher","DOI":"10.1177\/1357633X15582108"},{"key":"e_1_2_12_144_1","doi-asserted-by":"publisher","DOI":"10.2337\/dci20\u20100053"},{"key":"e_1_2_12_145_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl\u20102017\u2010312539"},{"key":"e_1_2_12_146_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjms.2017.07.011"},{"key":"e_1_2_12_147_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0179172"},{"key":"e_1_2_12_148_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.02.077"},{"key":"e_1_2_12_149_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2021.108833"},{"key":"e_1_2_12_150_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2015.12.007"},{"key":"e_1_2_12_151_1","doi-asserted-by":"publisher","DOI":"10.1097\/HCR.0b013e3181c565fe"},{"key":"e_1_2_12_152_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.117.006404"},{"key":"e_1_2_12_153_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.05.019"},{"key":"e_1_2_12_154_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.10.824"},{"key":"e_1_2_12_155_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.03.008"}],"container-title":["Diabetes, Obesity and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dom-pubs.pericles-prod.literatumonline.com\/doi\/pdf\/10.1111\/dom.15085","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T06:25:42Z","timestamp":1761891942000},"score":1,"resource":{"primary":{"URL":"https:\/\/dom-pubs.pericles-prod.literatumonline.com\/doi\/10.1111\/dom.15085"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,30]]},"references-count":154,"journal-issue":{"issue":"S3","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["10.1111\/dom.15085"],"URL":"https:\/\/doi.org\/10.1111\/dom.15085","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/DOM.15085\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.15085\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.15085\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.15085\/v1\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.15085\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.15085\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.15085\/v2\/review1","asserted-by":"object"}]},"ISSN":["1462-8902","1463-1326"],"issn-type":[{"value":"1462-8902","type":"print"},{"value":"1463-1326","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,30]]},"assertion":[{"value":"2023-01-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}