{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:36:52Z","timestamp":1790775412206,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T00:00:00Z","timestamp":1698710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To investigate glycaemic outcomes in youths and adults with type 1 diabetes with either MiniMed\u2122 780G or Tandem t:slim X2\u2122 control\u2010IQ automated insulin delivery (AID) systems and to evaluate clinical factors that migrate, mitigate the achievement of therapeutic goals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      This retrospective, real\u2010world, observational study was conducted in a specialized university type 1 diabetes centre with patients observed for 3\u201012\u2009months post\u2010initiation of an AID system. Primary outcomes were the percentage time in the target glucose range [TIR\n                      <jats:sub>70\u2010180 mg\/dl<\/jats:sub>\n                      (3.9\u201010\u2009mmol\/L)] as measured by continuous glucose monitoring, mean glucose management indicator (GMI) and glycated haemoglobin (HbA1c) levels.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Our study cohort consisted of 48 adolescents and 183 adults (55% females) aged 10\u201077\u2009years. The mean (95% confidence interval) TIR\n                      <jats:sub>70\u2010180 mg\/dl<\/jats:sub>\n                      after 30\u2009days was higher than baseline and by 14% points after 360\u2009days with 71.33% (69.4\u201073.2) (n\u2009=\u2009123,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.001). HbA1c levels decreased by 0.7% and GMI by 0.6% after 360\u2009days. The proportion of time spent &lt;70\u2009mg\/dl (3.9\u2009mmol\/L) was not significantly different from baseline. During follow\u2010up, 780G users had better continuous glucose monitoring results than control\u2010IQ users but similar HbA1c levels, and an increased risk of weight gain. Age at onset influenced TIR\n                      <jats:sub>70\u2010180 mg\/dl<\/jats:sub>\n                      in univariate analysis but there was no significant relationship after adjusting on explanatory variables. Baseline body mass index did not influence the performance of AID systems.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      This analysis showed the beneficial effects of two AID systems for people with type 1 diabetes across a broad spectrum of participant characteristics. Only half of the participants achieved international recommendations for glucose control with TIR\n                      <jats:sub>70\u2010180 mg\/dl<\/jats:sub>\n                      &gt;70%, HbA1c levels or GMI &lt;7%, which outlines the need to maintain strong educational and individual strategies.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.15344","type":"journal-article","created":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T03:53:35Z","timestamp":1698724415000},"page":"557-566","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Beneficial effects of automated insulin delivery over one\u2010year follow\u2010up in real life for youths and adults with type 1 diabetes irrespective of patient characteristics"],"prefix":"10.1111","volume":"26","author":[{"given":"Zo\u00e9","family":"Henry","sequence":"first","affiliation":[{"name":"Centre for Diabetes DIAB\u2010eCARE Hospices Civils de Lyon  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvie","family":"Villar Fimbel","sequence":"additional","affiliation":[{"name":"Centre for Diabetes DIAB\u2010eCARE Hospices Civils de Lyon  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Bendelac","sequence":"additional","affiliation":[{"name":"Centre for Diabetes DIAB\u2010eCARE Hospices Civils de Lyon  Lyon France"},{"name":"Department of paediatric Endocrinology and Diabetes Hospices Civils de Lyon  Bron France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Perge","sequence":"additional","affiliation":[{"name":"Department of paediatric Endocrinology and Diabetes Hospices Civils de Lyon  Bron France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0696-974X","authenticated-orcid":false,"given":"Charles","family":"Thivolet","sequence":"additional","affiliation":[{"name":"Centre for Diabetes DIAB\u2010eCARE Hospices Civils de Lyon  Lyon 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