{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T19:58:33Z","timestamp":1791575913237,"version":"4.3.4"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T00:00:00Z","timestamp":1705363200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100023233","name":"National Institute for Health and Care Research Applied Research Collaboration Oxford and Thames Valley","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100023233","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013373","name":"NIHR Oxford Biomedical Research Centre","doi-asserted-by":"publisher","award":["IS\u2010BRC\u20101215\u201020008"],"award-info":[{"award-number":["IS\u2010BRC\u20101215\u201020008"]}],"id":[{"id":"10.13039\/501100013373","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To test the feasibility and acceptability of a reduced\u2010carbohydrate dietary program, intended to reduce the risk of gestational diabetes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      Fifty\u2010one pregnant women at &lt;20\u2009weeks' gestation, with body mass index \u226530\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      , and a normal baseline oral glucose tolerance test (OGTT), were randomized 2:1 to an intervention or control group and followed\u2010up until delivery. The dietary intervention aimed at providing 130\u2013150\u2009g carbohydrate\/day. Feasibility outcomes assessed at 24\u201328\u2009weeks' gestation, included adoption of the reduced\u2010carbohydrate diet by the intervention group, and retention of all participants, assessed by completion of a second OGTT. Changes in glycemia, weight gain and dietary intake, and the maternal and neonatal outcomes were also assessed. Participants were interviewed about their experience of the intervention and the study.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Forty\u2010nine of 51 participants attended the follow\u2010up OGTT, a retention rate of 96% (95% confidence interval [CI] 86.8%\u201398.9%). In the intervention group, carbohydrate intake at follow\u2010up was 190.4 (95% CI 162.5\u2013215.6) g\/day, a reduction of \u221224.6 (95% CI \u221251.5\u20132.4) g\/day from baseline. Potentially favourable effects of the intervention on glucose control, weight gain and blood pressure were observed, but the study was not powered to detect significant differences in these. Participants found the intervention acceptable, and were content with the study processes, but some reported barriers to sustained adherence, mainly pertaining to competing priorities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Retention was high, suggesting the study processes are feasible, but the carbohydrate reduction in the intervention group was small, and did not meet progression criteria, limiting the likelihood of achieving the desired goal to prevent gestational diabetes. Trial registration number: ISRCTN16235884.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.15442","type":"journal-article","created":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T01:20:13Z","timestamp":1705454413000},"page":"1407-1420","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["<scp>REduced\u2010Carbohydrate<\/scp>\n                    intervention for managing Obesity and Reduction of gestational Diabetes (\n                    <scp>RECORD<\/scp>\n                    ): A randomized controlled feasibility trial"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6063-3307","authenticated-orcid":false,"given":"Moscho","family":"Michalopoulou","sequence":"first","affiliation":[{"name":"Nuffield Department of Primary Care Health Sciences University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan 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