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Fixed\/random\u2010effect models were used to calculate the odds ratios (ORs) and mean differences (MDs) with 95% confidence intervals (CIs) for the effect size analysis, with heterogeneity determined by\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      statistics. Subgroup analyses of different classes of hydrogel were also conducted.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 15 randomized controlled trials with 872 patients were eligible for the present analysis. Compared with conventional dressings, hydrogel dressings significantly improved the healing rate (OR 4.09, 95% CI 2.83 to 5.91), shortened the healing time (MD\u2009\u221211.38, 95% CI \u221213.11 to \u22129.66), enhanced granulation formation (MD\u2009\u22123.60, 95% CI \u22124.21 to \u22123.00) and epithelial formation (MD\u2009\u22122.82, 95% CI \u22123.19 to \u22122.46), and reduced the incidence of bacterial infection (OR\u20090.10, 95% CI 0.05 to 0.18).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The meta\u2010analysis showed that hydrogel dressings are more effective in treating DFU compared with conventional dressings.<\/jats:p>\n                  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