{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T00:01:01Z","timestamp":1773792061310,"version":"3.50.1"},"reference-count":44,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T00:00:00Z","timestamp":1712534400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["P30\u2010DK116073"],"award-info":[{"award-number":["P30\u2010DK116073"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100022690","name":"JDRF","doi-asserted-by":"publisher","award":["3\u2010SRA\u20102015\u2010125\u2010M\u2010R"],"award-info":[{"award-number":["3\u2010SRA\u20102015\u2010125\u2010M\u2010R"]}],"id":[{"id":"10.13039\/100022690","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1 TR001082"],"award-info":[{"award-number":["UL1 TR001082"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Type 1 diabetes (T1D) increases the risk of morbidity and mortality from cardiovascular disease, and insufficient sleep is prevalent. Emerging evidence suggests a link between sleep and cardiometabolic health, but this has not been examined across the lifespan in individuals with T1D. We aimed to examine associations between sleep and cardiometabolic health in adolescents and adults with T1D in a secondary analysis of data from a 4\u2010week double\u2010blind, random\u2010order, placebo\u2010controlled crossover trial of bromocriptine quick release (BCQR) therapy with a 4\u2010week washout in between conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Forty\u2010two adults (19\u201060\u2009years) and 42 adolescents (12\u201018\u2009years) with T1D &gt;9\u2009months completed 1\u2009week of home monitoring with wrist\u2010worn actigraphy to estimate sleep duration and continuous glucose monitoring, anthropometrics, arterial stiffness, magnetic resonance imaging (adolescents only), and fasting laboratory testing at each treatment phase.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Sixty\u2010two per cent of adolescents and 74% of adults obtained &lt;7\u2009h of sleep per night at baseline. After adjustment for age, sex and diabetes duration, baseline sleep &lt;7\u2009h per night was associated with a higher body mass index, a higher waist circumference, a higher systolic blood pressure, worse arterial stiffness and a lower estimated insulin sensitivity (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.05). When examined by age group, associations between sleep duration and cardiometabolic health outcomes remained significant, predominantly for adolescents. In adolescents only, wake time was significantly later (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.027) and time in bed was significantly longer with BCQR versus placebo (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.049).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Objectively measured sleep &lt;7\u2009h per night was prevalent in adolescents and adults with T1D and associated with poorer cardiometabolic health markers. Small changes in sleep were seen following BCQR treatment in adolescents only. Sleep may be an important and novel target for improving cardiometabolic health in individuals with T1D.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.15582","type":"journal-article","created":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T04:00:31Z","timestamp":1712548831000},"page":"2662-2672","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Sleep duration and association with cardiometabolic health in adolescents and adults with type 1 diabetes: Results from the\n                    <scp>BCQR\u2010T1D<\/scp>\n                    study"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4755-8151","authenticated-orcid":false,"given":"Stacey L.","family":"Simon","sequence":"first","affiliation":[{"name":"Department of Pediatrics University of Colorado Anschutz Medical Campus  Aurora Colorado 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USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uyen","family":"Truong","sequence":"additional","affiliation":[{"name":"Department of Cardiology Children's National Hospital  Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoshana S.","family":"Tell","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado Anschutz Medical Campus  Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy","family":"Vigers","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado Anschutz Medical Campus  Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy D.","family":"Baumgartner","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado Anschutz Medical Campus  Aurora Colorado 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