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In primary care, most CKD is caused by diabetes and\/or hypertension, but a substantial proportion of cases may have alternative causes. During the early stages, CKD is asymptomatic, and many people are unaware that they are living with the disease. Despite the lack of symptoms, CKD is associated with elevated risks of cardiovascular disease, progressive kidney disease, kidney failure and premature mortality. Risk reduction strategies are effective and cost\u2010effective but require early diagnosis through testing of the estimated glomerular filtration rate and albuminuria in high\u2010risk populations. Once diagnosed, the treatment of CKD centres around lifestyle interventions, blood pressure and glycaemic control, and preventative treatments for cardiovascular disease and kidney disease progression. Most patients with CKD should be managed with statins, renin\u2010angiotensin\u2010aldosterone system inhibitors and sodium\u2010glucose cotransporter\u20102 inhibitors. Additional treatment options to reduce cardiorenal risk are available in patients with diabetes, including glucagon\u2010like peptide\u20101 receptor agonists and non\u2010steroidal mineralocorticoid receptor antagonists. The Kidney Failure Risk Equation is a new tool that can support the identification of patients at high risk of progressive kidney disease and kidney failure and can be used to guide referrals to nephrology. This review summarizes the latest guidance relevant to managing adults with, or at risk of, CKD and provides practical advice for managing patients with CKD in primary care.<\/jats:p>","DOI":"10.1111\/dom.15625","type":"journal-article","created":{"date-parts":[[2024,5,3]],"date-time":"2024-05-03T06:05:15Z","timestamp":1714716315000},"page":"43-54","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Detecting and managing the patient with chronic kidney disease in primary care: A review of the latest guidelines"],"prefix":"10.1111","volume":"26","author":[{"given":"Kaitlin J.","family":"Mayne","sequence":"first","affiliation":[{"name":"School of Cardiovascular and Metabolic Health University of Glasgow  Glasgow UK"},{"name":"Glasgow Renal and Transplant Unit NHS Greater Glasgow and Clyde  Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Hanlon","sequence":"additional","affiliation":[{"name":"School of Health and Wellbeing University of Glasgow  Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6331-0178","authenticated-orcid":false,"given":"Jennifer S.","family":"Lees","sequence":"additional","affiliation":[{"name":"School of Cardiovascular and Metabolic Health University of Glasgow  Glasgow UK"},{"name":"Glasgow Renal and Transplant Unit NHS Greater Glasgow and Clyde  Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,5,3]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214\u2010109X(23)00570\u20103"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfs269"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12916\u2010021\u201002147\u20106"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2023.10.018"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.17002"},{"key":"e_1_2_7_7_1","volume-title":"National Institute for Health and Care Excellence. 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