{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T22:19:14Z","timestamp":1785449954307,"version":"3.56.0"},"reference-count":29,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T00:00:00Z","timestamp":1717372800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100001003","name":"Boehringer Ingelheim","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001003","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005205","name":"Janssen Research and Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005205","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011747","name":"Novo Nordisk Foundation Center for Basic Metabolic Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011747","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>The management of patients with type 2 diabetes is asynchronous, i.e. not coordinated in time, resulting in delayed access to care and low use of guideline\u2010directed medical therapy (GDMT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analysed consecutive patients assessed in the \u2018synchronized\u2019 DECIDE\u2010CV clinic. In this outpatient clinic, patients with type 2 diabetes and cardiovascular or chronic kidney disease are simultaneously assessed by an endocrinologist, cardiologist and nephrologist in the same visit. The primary outcome was use of GDMT before and after the assessment in the clinic, including sodium\u2010glucose cotransporter 2 inhibitors, glucagon\u2010like peptide 1 receptor agonists, renin\u2010angiotensin system blockers and mineralocorticoid receptor antagonists. Secondary outcomes included the baseline\u2010to\u2010last\u2010visit change in surrogate laboratory biomarkers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The first 232 patients evaluated in the clinic were included. The mean age was 67\u2009\u00b1\u200912\u2009years, 69% were men and 92% had diabetes. In total, 73% of patients had atherosclerotic cardiovascular disease, 65% heart failure, 56% chronic kidney disease and 59% had a urinary albumin\u2010to\u2010creatinine ratio \u226530\u2009mg\/g. There was a significant increase in the use of GDMT:sodium\u2010glucose cotransporter 2 inhibitors (from 44% to 87% of patients), glucagon\u2010like peptide 1 receptor agonists (from 8% to 45%), renin\u2010angiotensin system blockers (from 77% to 91%) and mineralocorticoid receptor antagonists (from 25% to 45%) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.01 for all). Among patients with paired laboratory data, glycated haemoglobin, urinary albumin\u2010to\u2010creatinine ratio and N\u2010terminal proB\u2010type natriuretic peptide levels significantly dropped from baseline (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.05 for all).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Joint assessment of patients with diabetes in a synchronized cardiometabolic clinic holds promise for enhancing GDMT use and has led to significant reductions in surrogate cardiovascular and renal laboratory biomarkers.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.15691","type":"journal-article","created":{"date-parts":[[2024,6,4]],"date-time":"2024-06-04T01:10:40Z","timestamp":1717463440000},"page":"3448-3457","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Utilizing synchronous care to improve cardiovascular and renal health among patients with type 2 diabetes: Proof\u2010of\u2010concept results from the\n                    <scp>DECIDE<\/scp>\n                    \u2010\n                    <scp>CV<\/scp>\n                    clinical programme"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1120-5461","authenticated-orcid":false,"given":"Pedro","family":"Marques","sequence":"first","affiliation":[{"name":"Division of Nephrology, Department of Medicine McGill University Health Center  Montreal Quebec Canada"},{"name":"DREAM\u2010CV Lab, Centre for Outcomes Research Research Institute of the McGill University Health Center  Montreal Quebec Canada"},{"name":"Division of Cardiology, Department of Medicine McGill University Health Center  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3368-247X","authenticated-orcid":false,"given":"Thomas A.","family":"Mavrakanas","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine McGill University Health Center  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian","family":"Guida","sequence":"additional","affiliation":[{"name":"DREAM\u2010CV Lab, Centre for Outcomes Research Research Institute of the McGill University Health Center  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tara","family":"G\u00e9d\u00e9on","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine McGill University Health Center  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anahita","family":"Emami","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine McGill University Health Center  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulkhaliq","family":"Alaamiri","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine McGill University Health Center  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Ho","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine McGill University Health Center  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elite","family":"Possik","sequence":"additional","affiliation":[{"name":"DREAM\u2010CV Lab, Centre for Outcomes Research Research Institute of the McGill University Health Center  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guang","family":"Zhang","sequence":"additional","affiliation":[{"name":"DREAM\u2010CV Lab, Centre for Outcomes Research Research Institute of the McGill University Health Center  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8326-7274","authenticated-orcid":false,"given":"Michael A.","family":"Tsoukas","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department of Medicine McGill University Health Center  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2346-8330","authenticated-orcid":false,"given":"Abhinav","family":"Sharma","sequence":"additional","affiliation":[{"name":"DREAM\u2010CV Lab, Centre for Outcomes Research Research Institute of the McGill University Health Center  Montreal Quebec Canada"},{"name":"Division of Cardiology, Department of Medicine McGill University Health Center  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,3]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)01301-6"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc16-0614"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.11111016"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2019.07.003"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.119.041022"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1811744"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2024816"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2204233"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2025845"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(18)30100-1"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2023.1266"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11886-022-01715-3"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/HCO.0000000000000892"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.940262"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.2854"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehad192"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2022.06.008"},{"key":"e_1_2_10_19_1","first-page":"47","article-title":"10. Cardiovascular disease and risk management: standards of Care in Diabetes\u20142024","volume":"47","author":"ElSayed NA","year":"2024","journal-title":"Diabetes Care"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.119.012797"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-150-9-200905050-00006"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.119.042685"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.18202"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc17-1096"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2019.0213"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2023.5627"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.120.007264"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/ckj\/sfac258"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000001186"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000001184"}],"container-title":["Diabetes, Obesity and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dom-pubs.pericles-prod.literatumonline.com\/doi\/pdf\/10.1111\/dom.15691","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T03:44:43Z","timestamp":1761882283000},"score":1,"resource":{"primary":{"URL":"https:\/\/dom-pubs.pericles-prod.literatumonline.com\/doi\/10.1111\/dom.15691"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,3]]},"references-count":29,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.1111\/dom.15691"],"URL":"https:\/\/doi.org\/10.1111\/dom.15691","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/DOM.15691\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.15691\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.15691\/v1\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.15691\/v1\/review4","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.15691\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.15691\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.15691\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.15691\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.15691\/v2\/review1","asserted-by":"object"}]},"ISSN":["1462-8902","1463-1326"],"issn-type":[{"value":"1462-8902","type":"print"},{"value":"1463-1326","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,3]]},"assertion":[{"value":"2024-03-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}