{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T12:34:43Z","timestamp":1792499683912,"version":"4.5.0"},"reference-count":22,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Prospective studies suggest that sleep\u2010disordered breathing enhances the risk of diabetes. However, it remains unclear whether diabetes could worsen sleep\u2010disordered breathing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The participants from Sleep Heart Health Study underwent two polysomnograms at a 5\u2010year interval. The relationship of baseline diabetes to change in the apnoea\u2010hypopnoea index (AHI) was examined based on general linear models, adjusting for demographics, lifestyles, history of hypertension, pulmonary function, length of follow\u2010up and baseline AHI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In total, 161 of the 2603 participants were diagnosed with diabetes at the first polysomnograms. Compared with participants without diabetes, those with diabetes had a higher baseline and larger increases in follow\u2010up AHI and obstructive apnoea index (oAI). Diabetes increased 2.52 events per hour (95% confidence interval 0.45\u20104.59;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.017) for AHI change and 1.13 events per hour (95% confidence interval 0.04\u20102.23;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.042) for oAI change, respectively. In addition, subgroup analysis suggested that the association was consistent across baseline obstructive sleep apnoea severity and body mass index groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Baseline diabetes was associated with worsening sleep\u2010disordered breathing over 5\u2009years, which mainly increased the change in AHI and oAI.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.15742","type":"journal-article","created":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T00:19:37Z","timestamp":1719879577000},"page":"3935-3939","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The association of diabetes with progression of sleep\u2010disordered breathing based on a prospective 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