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The effects of drugs on glucose metabolism have been reported frequently in recent years, and since abnormal glucose metabolism increases the risk of microvascular and macrovascular complications, metabolic disorders, and infection, clinicians need to pay close attention to these effects. A variety of common drugs can affect glucose metabolism and have different mechanisms of action. Hypertension is a common chronic cardiovascular disease that requires long\u2010term medication. Studies have shown that various antihypertensive drugs also have an impact on glucose metabolism. Among them, \u03b1\u2010receptor blockers, angiotensin\u2010converting enzyme inhibitors, angiotensin receptor blockers, and calcium channel blockers can improve insulin resistance, while \u03b2\u2010receptor blockers, thiazides and loop diuretics can impair glucose metabolism. 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