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We observed and analysed the systemic and oral disease indicators before and after treatment and clarified the indicators related to periodontal inflammation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A significant reduction in glycaemic and periodontal parameters, including glycated albumin levels and periodontal inflamed surface area (PISA), was observed after treatment. The changes in PISA per tooth, indicative of periodontal healing, exhibited a bimodal distribution; the patients were divided into two groups on this basis. Correlations were observed between the changes in PISA per tooth and fasting plasma glucose, acetoacetic acid, and beta\u2010hydroxybutyrate levels in the PISA\u2010improved group. Significantly lower levels of C\u2010peptide, coefficient of variation of R\u2010R interval, and ankle\u2010brachial pressure index were observed before treatment in the PISA non\u2010improved group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Glycaemic control treatment can effectively improve periodontitis in patients with type 2 diabetes, even in the absence of specific periodontal treatments. However, the periodontal responsiveness to glycaemic control treatment depends on the systemic condition of the patient.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.15835","type":"journal-article","created":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T23:48:21Z","timestamp":1723679301000},"page":"4684-4693","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Periodontal tissue susceptibility to glycaemic control in type 2 diabetes"],"prefix":"10.1111","volume":"26","author":[{"given":"Moe","family":"Inoue","sequence":"first","affiliation":[{"name":"Department of Preventive Dentistry Osaka University Graduate School of Dentistry  Suita Osaka Japan"},{"name":"Japan Society for the Promotion of Science  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akito","family":"Sakanaka","sequence":"additional","affiliation":[{"name":"Department of Preventive Dentistry Osaka 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