{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T22:46:11Z","timestamp":1790721971183,"version":"4.1.0"},"reference-count":52,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,9,2]],"date-time":"2024-09-02T00:00:00Z","timestamp":1725235200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2024,11]]},"abstract":"Abstract<\/jats:title>\n \n Aim<\/jats:title>\n The aim was to investigate whether COVID\u201019 increases new incidence of hypertension (HTN), chronic kidney disease (CKD) and diabetic ketoacidosis (DKA) in patients with type 1 diabetes (T1D) up to 40 months post\u2010infection.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods<\/jats:title>\n \n Three groups of patients from the Montefiore Health System in the Bronx (1 March 2020 to 1 July 2023) were studied: T1D patients hospitalized for COVID\u201019 (H\u2010COVID\u201019,\n n<\/jats:italic>\n \u2009=\u2009511), T1D patients with COVID\u201019 but not hospitalized for COVID\u201019 (NH\u2010COVID\u201019,\n n<\/jats:italic>\n \u2009=\u2009306) and T1D patients without a positive COVID\u201019 test on record (non\u2010COVID\u201019,\n n<\/jats:italic>\n \u2009=\u20091547). COVID\u201019 patients were those with a positive polymerase\u2010chain\u2010reaction test on record, and non\u2010COVID\u201019 patients were either tested negative or not tested on record. Cumulative incidences and adjusted hazard ratios (aHR) with 95% confidence intervals (CI) were computed with adjustment for competing risks.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Compared to non\u2010COVID\u201019 patients, both H\u2010COVID\u201019 (unadjusted 19.72% vs. 3.14%,\n p<\/jats:italic>\n \u2009<\u20090.001; aHR\u2009=\u20097.55 [3.33, 17.06],\n p<\/jats:italic>\n \u2009<\u20090.001) and NH\u2010COVID\u201019 (10.26% vs. 3.14%,\n p<\/jats:italic>\n \u2009=\u20090.004; aHR\u2009=\u20095.08 [2.19, 11.78],\n p<\/jats:italic>\n \u2009<\u20090.001) patients were more likely to develop new HTN. Compared to non\u2010COVID\u201019 patients, both H\u2010COVID\u201019 (11.41% vs. 1.14%,\n p<\/jats:italic>\n \u2009<\u20090.001; aHR\u2009=\u20099.76 [4.248, 22.25],\n p<\/jats:italic>\n \u2009<\u20090.001) and NH\u2010COVID\u201019 (7.69% vs. 1.14%,\n p<\/jats:italic>\n \u2009<\u20090.001; aHR\u2009=\u20096.54 [2.91, 14.67],\n p<\/jats:italic>\n \u2009<\u20090.001) patients were more likely to develop new CKD. Compared to non\u2010COVID\u201019 patients, both H\u2010COVID\u201019 (4.09% vs. 1.06%,\n p<\/jats:italic>\n \u2009<\u20090.001; aHR\u2009=\u200912.24 [4.09, 36.59],\n p<\/jats:italic>\n \u2009<\u20090.001) and NH\u2010COVID\u201019 (3.06% vs. 1.06%,\n p<\/jats:italic>\n \u2009=\u20090.035; aHR\u2009=\u200912.94 [4.09, 40.89],\n p<\/jats:italic>\n \u2009<\u20090.001) patients were more likely to develop new DKA at follow\u2010up.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n T1D patients with COVID\u201019 are at higher risk of developing new HTN, CKD and DKA compared to T1D patients without COVID\u201019.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/dom.15900","type":"journal-article","created":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T01:55:32Z","timestamp":1725328532000},"page":"5368-5375","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Patients with type 1 diabetes are at elevated risk of developing new hypertension, chronic kidney disease and diabetic ketoacidosis after\n COVID<\/scp>\n \u201019: Up to 40\u2009months\u2019 follow\u2010up"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-0748-3514","authenticated-orcid":false,"given":"Shiv","family":"Mehrotra\u2010Varma","sequence":"first","affiliation":[{"name":"Department of Radiology Albert Einstein College of Medicine and Montefiore Medical Centre New York City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin Y.","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Radiology Albert Einstein College of Medicine and Montefiore Medical Centre New York City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Montek Singh","family":"Boparai","sequence":"additional","affiliation":[{"name":"Department of Radiology Albert Einstein College of Medicine and Montefiore Medical Centre New York City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonya","family":"Henry","sequence":"additional","affiliation":[{"name":"Department of Radiology Albert Einstein College of Medicine and Montefiore Medical Centre New York City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6212-2906","authenticated-orcid":false,"given":"Stephen H.","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiology Albert Einstein College of Medicine and Montefiore Medical Centre New York City New York USA"},{"name":"Department of Surgery Beth Israel Deaconess Medical Centre and Harvard Medical School Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6403-2827","authenticated-orcid":false,"given":"Tim Q.","family":"Duong","sequence":"additional","affiliation":[{"name":"Department of Radiology Albert Einstein College of Medicine and Montefiore Medical Centre New York City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,2]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(20)30272-2"},{"issue":"1","key":"e_1_2_9_3_1","first-page":"87","article-title":"Higher rate of COVID\u201019 mortality in patients with type 1 than type 2 diabetes: a nationwide study","volume":"73","author":"Demirci I","year":"2022","journal-title":"Endokrynol pol"},{"issue":"3","key":"e_1_2_9_4_1","article-title":"COVID\u201019 and type 1 diabetes: concerns and challenges","volume":"91","author":"Iughetti L","year":"2020","journal-title":"Acta 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