{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T16:02:56Z","timestamp":1784736176086,"version":"3.55.0"},"reference-count":104,"publisher":"Wiley","issue":"S7","license":[{"start":{"date-parts":[[2024,10,16]],"date-time":"2024-10-16T00:00:00Z","timestamp":1729036800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003130","name":"Fonds Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["1800220N"],"award-info":[{"award-number":["1800220N"]}],"id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Continuous glucose monitoring (CGM) has led to a paradigm shift in the management of pregnant women with type 1 diabetes (T1D), with improved glycaemic control, less hypoglycaemia and fewer pregnancy complications. Data on CGM use in pregnant women with type 2 diabetes (T2D) are limited. A large randomized controlled trial (RCT) on CGM use in people with T2D in pregnancy is ongoing. Small studies on CGM use in women with gestational diabetes (GDM) have suggested improved glycaemic control and better qualification when insulin is needed. However, none of these studies was powered to evaluate pregnancy outcomes. Several large RCTs are ongoing in women with GDM. In addition to CGM, other technologies, such as advanced hybrid closed\u2010loop (AHCL) systems have further improved glycaemic management in people with T1D. AHCL therapy adapts insulin delivery via a predictive algorithm integrated with CGM and an insulin pump. A large RCT with the AHCL CamAPS\u00ae FX demonstrated a 10% increase in time in range compared to standard insulin therapy in a pregnant population with T1D. Recently, an RCT of an AHCL system not approved for use in pregnancy (780G MiniMed) has also demonstrated additional benefits of AHCL therapy compared to standard insulin therapy, with improved time in range overnight, less hypoglycaemia and improved treatment satisfaction. More evidence is needed on the impact of AHCL therapy on maternal and neonatal outcomes and on which glycaemic targets with CGM should be used in pregnant women with T2D and GDM. We review the current evidence on the use of CGM and AHCL therapy in pregnancy.<\/jats:p>","DOI":"10.1111\/dom.15999","type":"journal-article","created":{"date-parts":[[2024,10,16]],"date-time":"2024-10-16T05:18:06Z","timestamp":1729055886000},"page":"74-91","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Use of continuous glucose monitoring and hybrid closed\u2010loop therapy in pregnancy"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3325-0263","authenticated-orcid":false,"given":"Katrien","family":"Benhalima","sequence":"first","affiliation":[{"name":"Department of Endocrinology University Hospitals Leuven  Leuven Belgium"},{"name":"Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism KU Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer M.","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Manitoba  Winnipeg Manitoba Canada"},{"name":"Children's Hospital Research Institute of Manitoba  Winnipeg Manitoba Canada"},{"name":"Department of Medicine University of Calgary  Calgary Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,16]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(23)00116-X"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(20)30406-X"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.25.3.554"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc07-1066"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-011-2363-6"},{"key":"e_1_2_12_7_1","article-title":"Automated insulin delivery for pregnant women with type 1 diabetes: where do we stand?","author":"Benhalima K","year":"2024","journal-title":"J Diabetes Sci Technol"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc10-1113"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa042973"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0902430"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)00827-4"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.7573\/dic.2021-9-13"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc19-1459"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32400-5"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/dme.14528"},{"issue":"9","key":"e_1_2_12_16_1","article-title":"Continuous glucose monitoring versus self\u2010monitoring of blood glucose in type 2 diabetes mellitus: a systematic review with meta\u2010analysis","volume":"11","author":"Janapala RN","year":"2019","journal-title":"Cureus"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2013-4332"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/dme.13649"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/jmf.14.4.256.260"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.2337\/dci19-0028"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-019-4850-0"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.14273"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2303911"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(24)00089-5"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.a1680"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc12-2360"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.13310"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/dme.14046"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.9778\/cmajo.20200128"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2023.0548"},{"key":"e_1_2_12_31_1","unstructured":"Excellence NIfHaC.Diabetes in pregnancy: management from preconception to the postnatal period. 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