{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T05:15:14Z","timestamp":1787980514173,"version":"build-2784847793"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T00:00:00Z","timestamp":1738627200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Since the launch of semaglutide for weight loss (Wegovy\u00ae, SEMA\u2010WL) in late 2022, there has been a huge increase in new users of SEMA\u2010WL. We explored characteristics, treatment expectations and experienced effectiveness and side effects among Danish adults using SEMA\u2010WL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A questionnaire\u2010based survey was conducted from September to December 2023 across 29 Danish community pharmacies. During a 10\u2010day period, pharmacies invited consecutive individuals aged \u226518\u2009years redeeming a prescription on SEMA\u2010WL to complete an electronic questionnaire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 1013 individuals were invited to study participation of which 55% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009559) accepted. Users of SEMA\u2010WL were primarily female (78%,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009434) and middle\u2010aged adults (36\u201365\u2009years; 76%,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009423), with a median body mass index of 36 (interquartile range [IQR] 32\u201340) at treatment initiation. Two in three users had personally asked their general practitioner to initiate treatment (70%,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009393). Four in ten users had not discussed expected treatment duration with their general practitioner (42%,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009237), almost half (46%,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009258) expected treatment for a limited time period, while only 11% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200964) expected lifelong treatment. Self\u2010reported median weight loss was 5.3% (IQR 3.2\u20138.5) for users treated for &lt;3\u2009months, 10% (IQR 8.2\u201314) for 3\u20135\u2009months of treatment and 17% (IQR 13\u201321) for those treated for &gt;5\u2009months. More than half of users (59%,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009330) had experienced side effects, most commonly nausea (35%,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009193) and constipation (29%,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009160).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study provides valuable insights into the characteristics, treatment expectations and effects experienced by Danish adult users of SEMA\u2010WL.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.16222","type":"journal-article","created":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T00:23:27Z","timestamp":1738715007000},"page":"2214-2222","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Survey among adult users of semaglutide for weight loss in Denmark: User characteristics, treatment expectations and experienced effects"],"prefix":"10.1111","volume":"27","author":[{"given":"Malene Svoldgaard","family":"S\u00f8rensen","sequence":"first","affiliation":[{"name":"Hospital Pharmacy Funen Odense University Hospital  Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9314-5679","authenticated-orcid":false,"given":"Anton","family":"Potteg\u00e5rd","sequence":"additional","affiliation":[{"name":"Hospital Pharmacy Funen Odense University Hospital  Odense Denmark"},{"name":"Clinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health University of Southern Denmark  Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5750-8911","authenticated-orcid":false,"given":"Nanna Elman","family":"Andersen","sequence":"additional","affiliation":[{"name":"Hospital Pharmacy Funen Odense University Hospital  Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9135-3474","authenticated-orcid":false,"given":"Reimar W.","family":"Thomsen","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology Aarhus University and Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2121-6252","authenticated-orcid":false,"given":"Carina","family":"Lundby","sequence":"additional","affiliation":[{"name":"Hospital Pharmacy Funen Odense University Hospital  Odense Denmark"},{"name":"Clinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health University of Southern Denmark  Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,4]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"World Health Organization.Obesity and overweight.https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/obesity-and-overweight2024Accessed August 27 2024."},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41569\u2010023\u201000847\u20105"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591\u2010022\u201002026\u20104"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.14725"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S456170"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmacy9020114"},{"key":"e_1_2_9_8_1","unstructured":"Pro.medicin.dk.Wegovy\u00ae Flextouch\u00ae.https:\/\/pro.medicin.dk\/Medicin\/Praeparater\/102472024Accessed October 18 2024."},{"key":"e_1_2_9_9_1","unstructured":"MadsenH EnnisZN ThomsenJL.Behandling af overv\u00e6gt hos voksne i almen praksis. L\u00e6gemidler skal bruges med omtanke. In: Ration. Farmakoter. Sundhedsstyrelsen.https:\/\/www.sst.dk\/\u2010\/media\/Udgivelser\/2023\/Rationel\u2010farmakoterapi\/4\/IRF\u2010Maanedsblad\u2010nr\u20104\u20102023.ashx2023Accessed August 22 2023."},{"key":"e_1_2_9_10_1","unstructured":"Sygeforsikring Danmark.dNYT. Information fra Sygeforsikring Danmark.https:\/\/www.sygeforsikring.dk\/files\/media\/pdf\/d-nyt_2_2023.pdf2023Accessed October 18 2024."},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2008.08.010"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sapharm.2019.12.021"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcpt.13837"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcpt.12762"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102458\u201011\u2010513"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/1049732319889354"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc24\u20101082"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2032183"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.1831"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.3224"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/cob.12666"},{"key":"e_1_2_9_22_1","unstructured":"Ugeskrift for L\u00e6ger.Wegovy i almen praksis: Det er helt vildt som det har forandret mit arbejdsliv.https:\/\/ugeskriftet.dk\/nyhed\/wegovy\u2010i\u2010almen\u2010praksis\u2010det\u2010er\u2010helt\u2010vildt\u2010som\u2010det\u2010har\u2010forandret\u2010mit\u2010arbejdsliv?utm_campaign=&utm_medium=Journalist&utm_source=Newsletter2019Accessed October 18 2024."}],"container-title":["Diabetes, Obesity and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dom-pubs.pericles-prod.literatumonline.com\/doi\/pdf\/10.1111\/dom.16222","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T06:53:41Z","timestamp":1761893621000},"score":1,"resource":{"primary":{"URL":"https:\/\/dom-pubs.pericles-prod.literatumonline.com\/doi\/10.1111\/dom.16222"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,4]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1111\/dom.16222"],"URL":"https:\/\/doi.org\/10.1111\/dom.16222","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/DOM.16222\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.16222\/v1\/review4","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.16222\/v1\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.16222\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.16222\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.16222\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.16222\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.16222\/v2\/decision1","asserted-by":"object"}]},"ISSN":["1462-8902","1463-1326"],"issn-type":[{"value":"1462-8902","type":"print"},{"value":"1463-1326","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,4]]},"assertion":[{"value":"2024-11-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}