{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T15:01:56Z","timestamp":1789398116340,"version":"build-2803163510"},"reference-count":39,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,3,18]],"date-time":"2025-03-18T00:00:00Z","timestamp":1742256000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100015769","name":"Dexcom","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015769","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Continuous glucose monitoring (CGM) improves glycaemic control and reduces hypoglycaemia in type 1 and 2 diabetes, but its role in managing diabetes in chronic pancreatitis is unknown. We aimed to investigate the effect of CGM compared to self\u2010monitoring of blood glucose (SMBG) on hypoglycaemia and glycaemic control in patients with chronic pancreatitis and insulin\u2010treated diabetes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>In a randomised, open\u2010label, crossover trial, 30 participants with chronic pancreatitis and insulin\u2010treated diabetes were randomised to 50\u2009days of CGM or SMBG, separated by a 20\u2010day washout period. The primary endpoint was time in level 2 hypoglycaemia (&lt;3.0\u2009mmol\/L). Secondary endpoints included additional CGM metrics, HbA1c, daily insulin dose, questionnaires, and safety outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Twenty\u2010nine participants completed the trial (mean age 64.4 \u00b1\u20098.8\u2009years; 22 men [75.9%]). There was a numerical reduction in time spent in level 2 hypoglycaemia with CGM compared to SMBG (mean difference \u22120.36%, 95% confidence interval (CI) \u22120.78% to 0.06%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.09). CGM improved time in range (3.9\u201310.0\u2009mmol\/L; mean difference 7.46%, 95% CI 1.67% to 13.25%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01), reduced time above range (&gt;10.0\u2009mmol\/L; mean difference \u22126.55%, 95% CI \u221212.59% to \u22120.51%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04), and reduced time below range (&lt;3.9\u2009mmol\/L; mean difference \u22120.91%, 95% CI \u22121.79% to \u22120.03%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04) compared to SMBG. No differences were observed for the safety endpoints.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In patients with chronic pancreatitis and insulin\u2010treated diabetes, CGM increased time in range and reduced time above and below range. These findings highlight the potential of CGM in improving glycaemic control.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.16356","type":"journal-article","created":{"date-parts":[[2025,3,18]],"date-time":"2025-03-18T06:55:21Z","timestamp":1742280921000},"page":"3379-3388","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Efficacy and safety of continuous glucose monitoring on glycaemic control in patients with chronic pancreatitis and insulin\u2010treated diabetes: A randomised, open\u2010label, crossover trial"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1120-8144","authenticated-orcid":false,"given":"Line","family":"Davidsen","sequence":"first","affiliation":[{"name":"Centre for Pancreatic Diseases and Mech\u2010Sense, Department of Gastroenterology and Hepatology Aalborg University Hospital  Aalborg Denmark"},{"name":"Department of Clinical Medicine Aalborg University  Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3484-7571","authenticated-orcid":false,"given":"Simon Lebech","family":"Cichosz","sequence":"additional","affiliation":[{"name":"Department of Health Science and Technology Aalborg University  Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter Bisgaard","family":"St\u00e6hr","sequence":"additional","affiliation":[{"name":"Department of Cardiology North Denmark Regional Hospital  Hj\u00f8rring Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Vestergaard","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine Aalborg University  Aalborg Denmark"},{"name":"Steno Diabetes Centre North Denmark Aalborg University Hospital  Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asbj\u00f8rn M.","family":"Drewes","sequence":"additional","affiliation":[{"name":"Centre for Pancreatic Diseases and Mech\u2010Sense, Department of Gastroenterology and Hepatology Aalborg University Hospital  Aalborg Denmark"},{"name":"Department of Clinical Medicine Aalborg University  Aalborg Denmark"},{"name":"Steno Diabetes Centre North Denmark Aalborg University Hospital  Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filip Krag","family":"Knop","sequence":"additional","affiliation":[{"name":"Center for Clinical Metabolic Research Gentofte Hospital, University of Copenhagen  Hellerup Denmark"},{"name":"Clinical Research Steno Diabetes Center Copenhagen, University of Copenhagen  Herlev Denmark"},{"name":"Department of Clinical Medicine Faculty of Health and Medical Sciences, University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6649-8644","authenticated-orcid":false,"given":"Morten Hasselstr\u00f8m","family":"Jensen","sequence":"additional","affiliation":[{"name":"Department of Health Science and Technology Aalborg University  Aalborg Denmark"},{"name":"Data Science Novo Nordisk A\/S  S\u00f8borg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00f8ren Schou","family":"Olesen","sequence":"additional","affiliation":[{"name":"Centre for Pancreatic Diseases and Mech\u2010Sense, Department of Gastroenterology and Hepatology Aalborg University Hospital  Aalborg Denmark"},{"name":"Department of Clinical Medicine Aalborg University  Aalborg 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