{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:42:45Z","timestamp":1772160165837,"version":"3.50.1"},"reference-count":9,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T00:00:00Z","timestamp":1758153600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T00:00:00Z","timestamp":1758153600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100009068","name":"University of Bern","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009068","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>The FreeStyle Libre 3 (FSL3) continuous glucose monitoring (CGM) system provides both auto\u2010logged glucose values (AL) and current displayed glucose values (CUR). These values are often assumed to be interchangeable; however, discrepancies and their clinical relevance remain underexplored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>Data from a 15\u2010day study in 24 study participants wearing FSL3 were analysed, including three in\u2010clinic sessions with glycaemic excursions during which CUR values were retrieved every 15\u2009min by study personnel. Paired AL and CUR readings were compared using descriptive statistics, Wilcoxon signed\u2010rank tests, and mean absolute relative difference (MARD) calculations. Display errors defined as instances where the app showed an error message instead of a CUR value were analysed using linear mixed\u2010effects models to assess associations with glucose level and rate of change (RoC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      CUR values were comparable to AL in general (mean difference: \u22121.2\u2009\u00b1 6.4\u2009mg\/dL), but slightly lower in the hypoglycaemic range. Discrepancies exceeding \u00b110\u2009mg\/dL occurred in about 10% of cases. MARD was comparable between AL (9.7%) and CUR (10.1%), with greater deviation in hypoglycaemia. Display errors (3.9%) occurred more often at higher glucose levels (mean AL difference: +91.9\u2009mg\/dL) and during rapid fluctuations (mean absolute RoC difference: +1.52\u2009mg\/dL\/min; both\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Although differences between AL and CUR were generally small, they were systematic and more pronounced in critical contexts like hypoglycaemia and rapid glucose change. Recognising these patterns may improve CGM data interpretation and alignment between user actions, provider decisions, and automated systems. These differences can reclassify readings across clinical thresholds, affecting patient\u2013clinician alignment despite small average biases.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.70140","type":"journal-article","created":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T05:33:16Z","timestamp":1758259996000},"page":"7367-7373","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Discrepancies between current displayed and auto\u2010logged glucose values in\n                    <scp>FreeStyle<\/scp>\n                    Libre 3: Implications for clinical interpretation"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9459-875X","authenticated-orcid":false,"given":"Lilian","family":"Witthauer","sequence":"first","affiliation":[{"name":"Department of Diabetes, Endocrinology, Nutritional Medicine and Metabolism, Inselspital, Bern University Hospital University of Bern  Bern Switzerland"},{"name":"Diabetes Center Berne  Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7317-3955","authenticated-orcid":false,"given":"Camilo","family":"Mendez","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Endocrinology, Nutritional Medicine and Metabolism, Inselspital, Bern University Hospital University of Bern  Bern Switzerland"},{"name":"Diabetes Center Berne  Bern Switzerland"},{"name":"Graduate School for Cellular and Biomedical Sciences University of Bern  Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9970-2162","authenticated-orcid":false,"given":"Jos\u00e9","family":"Garcia\u2010Tirado","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Endocrinology, Nutritional Medicine and Metabolism, Inselspital, Bern University Hospital University of Bern  Bern Switzerland"},{"name":"Diabetes Center Berne  Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2150-3160","authenticated-orcid":false,"given":"Manuel","family":"Eichenlaub","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Diabetes\u2010Technologie Forschungs\u2010 und Entwicklungsgesellschaft mbH an der Universit\u00e4t Ulm  Ulm Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3280-2369","authenticated-orcid":false,"given":"Delia","family":"Waldenmaier","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Diabetes\u2010Technologie Forschungs\u2010 und Entwicklungsgesellschaft mbH an der Universit\u00e4t Ulm  Ulm Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4629-7754","authenticated-orcid":false,"given":"Stefan","family":"Pleus","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Diabetes\u2010Technologie Forschungs\u2010 und Entwicklungsgesellschaft mbH an der Universit\u00e4t Ulm  Ulm Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0406-9529","authenticated-orcid":false,"given":"Guido","family":"Freckmann","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Diabetes\u2010Technologie Forschungs\u2010 und Entwicklungsgesellschaft mbH an der Universit\u00e4t Ulm  Ulm Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,18]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213\u20108587(16)30193\u20100"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.42545"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13300\u2010023\u201001385\u20106"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc25\u20100129"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/19322968251315459"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc18\u20101150"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/19322968251317526"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/19322968251336221"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/1932296817733095"}],"container-title":["Diabetes, Obesity and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dom-pubs.pericles-prod.literatumonline.com\/doi\/pdf\/10.1111\/dom.70140","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dom-pubs.pericles-prod.literatumonline.com\/doi\/full-xml\/10.1111\/dom.70140","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dom-pubs.pericles-prod.literatumonline.com\/doi\/pdf\/10.1111\/dom.70140","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T15:31:31Z","timestamp":1771342291000},"score":1,"resource":{"primary":{"URL":"https:\/\/dom-pubs.pericles-prod.literatumonline.com\/doi\/10.1111\/dom.70140"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,18]]},"references-count":9,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1111\/dom.70140"],"URL":"https:\/\/doi.org\/10.1111\/dom.70140","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/DOM.70140\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70140\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70140\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70140\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70140\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70140\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70140\/v1\/decision1","asserted-by":"object"}]},"ISSN":["1462-8902","1463-1326"],"issn-type":[{"value":"1462-8902","type":"print"},{"value":"1463-1326","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,18]]},"assertion":[{"value":"2025-07-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}