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Neuropsychological assessments were conducted at 6, 18, 30, and 42\u2009months. Change in the composite cognitive Z\u2010score served as the primary endpoint. Metabolic control was evaluated using continuous glucose monitoring. Between\u2010group differences at 42\u2009months were analysed using mixed\u2010effects models for repeated measures (\n                      <jats:styled-content style=\"fixed-case\">MMRM<\/jats:styled-content>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 42 participants (22 intervention, 20 control) were analysed. The\n                      <jats:styled-content style=\"fixed-case\">MMRM<\/jats:styled-content>\n                      did not show significant between\u2010group differences in the composite cognitive Z\u2010score at 42\u2009months (0.19; 95% confidence intervals [\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      ]: \u22120.14 to 0.52). However, the trail making test part A (\u221218.0; 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : \u221228.7 to \u22127.19) and part B (\u221226.2; 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : \u221250.5 to \u22121.91) showed that the intervention had significant benefits. A significant between\u2010group difference was also observed in the change in %time range 70\u2013180\u2009mg\/\n                      <jats:styled-content style=\"fixed-case\">dL<\/jats:styled-content>\n                      (16.2; 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 0.96\u201331.5).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Multidomain interventions appear to provide sustained benefits for executive function and metabolic control in older adults with type 2 diabetes and\n                      <jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>\n                      . Further studies should be performed to validate these findings.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.70431","type":"journal-article","created":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T07:07:55Z","timestamp":1767942475000},"page":"2350-2361","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Long\u2010term effects of a multidomain intervention on cognitive function and metabolic control in older adults with type 2 diabetes and mild cognitive impairment: A 42\u2010month follow\u2010up of the J\u2010\n                    <scp>MIND<\/scp>\n                    \u2010Diabetes study"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6418-0755","authenticated-orcid":false,"given":"Taiki","family":"Sugimoto","sequence":"first","affiliation":[{"name":"Department of Prevention and Care Science Research Institute, National Center for 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