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We evaluated whether the 1\u2010h glucose on the postpartum OGTT predicts dysglycaemia and metabolic changes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Secondary analysis of a multicentre randomised controlled trial evaluating a mobile\u2010based lifestyle intervention early postpartum in women with prediabetes after GDM (WHO 2013 criteria). Women were categorised by their 1\u2010h glucose value at 3\u2009months postpartum (baseline), using 8.6\u2009mmol\/L as the high\u2010risk threshold following International Diabetes Federation criteria. A subgroup underwent a repeat OGTT at 12\u2009months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At 3\u2009months postpartum, 28.0% (334\/1193) had dysglycaemia based on the 2\u2010h OGTT and 34.2% (408\/1193) based on the 1\u2010h glucose value. Women identified only by the 1\u2010h glucose were less insulin resistant but showed similar \u03b2\u2010cell dysfunction compared with those identified only by the 2\u2010h OGTT. Among 166 women with baseline prediabetes defined by the 2\u2010h OGTT, 63.9% (106) had 1\u2010h glucose \u2265\u20098.6\u2009mmol\/L. At 1\u2009year postpartum, women with baseline 1\u2010h glucose \u2265\u20098.6\u2009mmol\/L accounted for all eight (7.3%) diagnoses of type 2 diabetes (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.036), more dysglycaemia (61.5 vs. 40.4%, p\u2009=\u20090.010), greater \u03b2\u2010cell impairment (lower ISSI\u20102,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001) and greater insulin resistance (lower Matsuda,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.049) compared with those with 1\u2010h glucose &lt;\u20098.6\u2009mmol\/L.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In women with a recent history of GDM and subsequent prediabetes, a 1\u2010h glucose value \u2265\u20098.6\u2009mmol\/L in early postpartum was associated with an increased risk for future type 2 diabetes, greater insulin resistance and impaired \u03b2\u2010cell function, supporting its potential value as an early marker of metabolic risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>MELINDA Trial, NCT03559621<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.70634","type":"journal-article","created":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T06:50:58Z","timestamp":1773125458000},"page":"4619-4629","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The One\u2010Hour Oral Glucose Tolerance Test to Predict Glucose Intolerance Postpartum in Women With Prior Gestational Diabetes"],"prefix":"10.1111","volume":"28","author":[{"given":"Niels","family":"Bochanen","sequence":"first","affiliation":[{"name":"Department of 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