{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T04:02:41Z","timestamp":1780459361920,"version":"3.54.1"},"reference-count":34,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:00:00Z","timestamp":1773014400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:00:00Z","timestamp":1773014400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004191","name":"Novo Nordisk","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004191","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>The objective was to characterise Finnish adults with type 1 diabetes (T1D) and to explore associations between known risk factors, comorbidities and mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Individuals with T1D in 2014\u20132021 were identified from national health care registers, and data on medication and comorbidities were combined with laboratory measurements from hospital data lakes. Comorbidity and risk\u2010factor associations were examined using Cox regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We identified 35\u2009574 adults with T1D. The proportion of individuals aged over 70\u2009years increased during the study period from 7.1% to 12.4% and the proportion of insulin pump users from 10% to 17%. Mean haemoglobin A1c (HbA1c) decreased by 1.7\u2009mmol\/mol (0.2%) and mean low\u2010density lipoprotein cholesterol (LDL\u2010c) by 0.2\u2009mmol\/L (7.7\u2009mg\/dL) from 2014 to 2021. The proportion of individuals with HbA1c &gt;\u200975\u2009mmol\/mol (&gt;\u20099.0%) reduced slightly (4%\u2010points); this improvement was more prominent in insulin pump users (9%\u2010points). Ketoacidosis was most common in young adults. Prevalence of chronic kidney disease (CKD) increased from 140 (95% CI 136\u2013145) to 168 (95% CI 163\u2013172) per 1000 persons during the study period (\n                      <jats:italic>p<\/jats:italic>\n                      \u2010trend &lt;\u20090.001). CKD and vascular disease resulted in a multifold increase in the mortality risk, whereas lipid\u2010lowering and antihypertensive medications reduced this risk (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001 for all).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The proportion of elderly with T1D is increasing, with no concomitant increase in vascular events. Insulin pump therapy has become more common without a concomitant increase in ketoacidosis incidence. HbA1c and LDL\u2010c levels improved during the study. Finnish data indicate a shift in T1D demographics, characterised by improved survival, while rates of diabetes\u2010specific comorbidities remain stable.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.70641","type":"journal-article","created":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T06:47:59Z","timestamp":1773125279000},"page":"4683-4695","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Demographic Change in Prevalent Type 1 Diabetes Adult Population, and Association of Risk Factors With Comorbidities and Mortality\u2014Results From the Finnish Diabetes Control Study\n                    <scp>FinDiCon<\/scp>"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-7367-4773","authenticated-orcid":false,"given":"Hannu","family":"Vessari","sequence":"first","affiliation":[{"name":"Novo Nordisk  Espoo 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