{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:25:51Z","timestamp":1787066751266,"version":"build-2736575974"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T00:00:00Z","timestamp":1774310400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T00:00:00Z","timestamp":1774310400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Scientific evidence on the impact of the female hormonal cycle on glycemic control in type 1 diabetes (T1D) remains limited. This study aimed to evaluate variations in glycemic control and insulin requirements throughout the menstrual cycle in women with T1D using an automated insulin delivery (AID) system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>An observational cohort study was conducted in women with T1D using the MiniMed 780G AID system. Continuous glucose monitoring (CGM) and insulin delivery data were analysed and compared between the late luteal phase (LLP) (Days \u22127 to \u22121) and the early follicular phase (EFP) (Days 1\u20137) across up to three cycles per participant.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 48\u2009cycles from 17 women were analysed (mean age 39.9\u2009\u00b1\u20096.3\u2009years; diabetes duration 30.1\u2009\u00b1\u20099.7\u2009years; BMI 25.7\u2009\u00b1\u20093.6\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ). During the LLP, participants showed a lower percentage of time in range (%TIR: 80.7% vs. 82.7%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05) and higher time above range (%TAR: 17.3% vs. 14.6%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01) and mean glucose (141 vs. 135\u2009mg\/dL,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01). In contrast, % time below range (%TBR) was higher during the EFP (2.8% vs. 2.0%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01). The total daily insulin dose (TDD) increased during the LLP (33.1 vs. 32.0\u2009units,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05), mainly due to higher prandial insulin (19.5 vs. 18.6\u2009units), without significant differences in basal or autocorrection doses.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Women with T1D using an AID system demonstrated phase\u2010dependent differences in glycemic control, with lower time in range and greater hyperglycemia during the LLP and a higher susceptibility to hypoglycemia during the early follicular phase, accompanied by higher prandial insulin requirements.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.70673","type":"journal-article","created":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T04:58:46Z","timestamp":1774414726000},"page":"4884-4889","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Glycemic Control During the Menstrual Cycle in Women With Type 1 Diabetes: Performance of an Automated Insulin Delivery System"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-7780-9120","authenticated-orcid":false,"given":"Tatiana Rojas","family":"L\u00f3pez","sequence":"first","affiliation":[{"name":"Department of Endocrinology Hospital Universitario La Paz  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel Lozano","family":"Acosta","sequence":"additional","affiliation":[{"name":"Department of Endocrinology Hospital Universitario La Paz  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz Barquiel","family":"Alcal\u00e1","sequence":"additional","affiliation":[{"name":"Department of Endocrinology Hospital Universitario La Paz  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oscar Moreno","family":"Dominguez","sequence":"additional","affiliation":[{"name":"Department of Endocrinology Hospital Universitario La Paz  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena Garc\u00eda P\u00e9rez","family":"de Sevilla","sequence":"additional","affiliation":[{"name":"Department of Endocrinology Hospital Universitario La Paz  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia Hillman","family":"Gadea","sequence":"additional","affiliation":[{"name":"Department of Endocrinology Hospital Universitario La Paz  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noem\u00ed Gonz\u00e1lez P\u00e9rez","family":"de Villar","sequence":"additional","affiliation":[{"name":"Department of Endocrinology Hospital Universitario La Paz  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,24]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/19322968221080199"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/1932296815608400"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2006.0004"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464\u20105491.1995.tb00462.x"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464\u20105491.1990.tb01309.x"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph20042772"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/jpm13020374"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medcle.2016.05.034"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213\u20108587(23)00286\u20103"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41746\u2010023\u201000884\u2010x"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2010\u20100702"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc12\u20102248"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1089\/1520915041705875"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgac443"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcjd.2024.06.004"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.15891"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2023.0571"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2021.0431"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2024.0522"},{"key":"e_1_2_11_21_1","first-page":"1543","volume-title":"43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","author":"Diaz J. 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