{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T04:01:33Z","timestamp":1780459293357,"version":"3.54.1"},"reference-count":45,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:00:00Z","timestamp":1773878400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:00:00Z","timestamp":1773878400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100023731","name":"Consejer\u00eda de Salud y Consumo, Junta de Andaluc\u00eda","doi-asserted-by":"publisher","award":["RHJ\u20100098\u20102024"],"award-info":[{"award-number":["RHJ\u20100098\u20102024"]}],"id":[{"id":"10.13039\/501100023731","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","award":["BG22\/00075"],"award-info":[{"award-number":["BG22\/00075"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","award":["FPU18\/03357"],"award-info":[{"award-number":["FPU18\/03357"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","award":["FPU21\/01161"],"award-info":[{"award-number":["FPU21\/01161"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","award":["FPU22\/01631"],"award-info":[{"award-number":["FPU22\/01631"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","award":["FPU23\/02158"],"award-info":[{"award-number":["FPU23\/02158"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016970","name":"Consejer\u00eda de Econom\u00eda, Conocimiento, Empresas y Universidad, Junta de Andaluc\u00eda","doi-asserted-by":"publisher","award":["A\u2010CTS\u2010516\u2010UGR20"],"award-info":[{"award-number":["A\u2010CTS\u2010516\u2010UGR20"]}],"id":[{"id":"10.13039\/100016970","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017266","name":"Gobierno de Navarra","doi-asserted-by":"publisher","award":["0011\u20101365\u20102021\u201000070"],"award-info":[{"award-number":["0011\u20101365\u20102021\u201000070"]}],"id":[{"id":"10.13039\/501100017266","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009708","name":"Novo Nordisk Fonden","doi-asserted-by":"publisher","award":["NNF23SA0084103"],"award-info":[{"award-number":["NNF23SA0084103"]}],"id":[{"id":"10.13039\/501100009708","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001648","name":"European Foundation for the Study of Diabetes","doi-asserted-by":"publisher","award":["0094134"],"award-info":[{"award-number":["0094134"]}],"id":[{"id":"10.13039\/501100001648","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["HORIZONEIC\u20102023\u2010PATHFINDERCHALLENGES\u201001\u2010101161509"],"award-info":[{"award-number":["HORIZONEIC\u20102023\u2010PATHFINDERCHALLENGES\u201001\u2010101161509"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI24\/01360"],"award-info":[{"award-number":["PI24\/01360"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To investigate how sleep features influence next\u2010day diurnal glucose homeostasis and vice versa in free\u2010living adults at risk of type 2 diabetes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      This observational repeated\u2010measures study included 388 adults aged 25\u201365\u2009years (50% women) with overweight or obesity (BMI \u2265\u200925.0\u2013&lt;\u200940.0\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ). Sleep and glucose homeostasis were simultaneously assessed over 14\u2009days using wrist\u2010worn accelerometers and continuous glucose monitors. Linear mixed models evaluated day\u2010level associations between sleep metrics\u2014wake\u2010up time, sleep period time (i.e., time from sleep onset to wake\u2010up) and sleep efficiency ([total sleep time\/sleep period time]\u2009\u00d7\u2009100)\u2014and diurnal glucose metrics, including mean glucose and its standard deviation (glycaemic variability).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We analysed 3942 valid person\u2010days. Each 1% increase in sleep efficiency was associated with lower next\u2010day mean glucose (B [95% CI]\u2009=\u2009\u22120.05 [\u22120.08, \u22120.01] mg\/dL;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007). Each 1\u2009h delay in wake\u2010up time was linked to reduced next\u2010day glucose variability (\u22120.24 [\u22120.38, \u22120.10] mg\/dL;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001). Conversely, each 1\u2009mg\/dL increase in daytime mean glucose was associated with later wake\u2010up time (0.008 [0.002, 0.014]\u2009h;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.008), longer sleep period time (0.006 [0.000, 0.012] h;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.039) and lower sleep efficiency (\u22120.05% [\u22120.08%, \u22120.01%] %;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005) the subsequent night. Each 1\u2009mg\/dL increase in glucose variability was associated with earlier wake\u2010up time (\u22120.02 [\u22120.03, \u22120.01]\u2009h;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study provides evidence that sleep and glucose dynamics are temporally associated in free\u2010living adults at risk of type 2 diabetes. These findings underscore the potential of combining sleep and glucose metrics to inform cardiometabolic risk prevention strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.70675","type":"journal-article","created":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T08:17:38Z","timestamp":1773908258000},"page":"4890-4900","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sleep Efficiency Predicts Next\u2010Day Glycaemia and Daytime Glycaemia Influences Sleep in Free\u2010Living Adults at Risk of Type 2 Diabetes"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6135-9848","authenticated-orcid":false,"given":"Antonio","family":"Clavero\u2010Jimeno","sequence":"first","affiliation":[{"name":"Department of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS) University of Granada  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8072-0116","authenticated-orcid":false,"given":"Juan J.","family":"Martin\u2010Olmedo","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Medicine, Sport and Health University Research Institute (iMUDS) University of Granada  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0366-6935","authenticated-orcid":false,"given":"Jairo H.","family":"Migueles","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS) University of Granada  Granada Spain"},{"name":"Department of Global Public Health Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7682-8336","authenticated-orcid":false,"given":"Alba","family":"Camacho\u2010Cardenosa","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS) University of Granada  Granada Spain"},{"name":"Instituto de Investigaci\u00f3n Biosanitaria de Granada (ibs. GRANADA)  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-9737-2666","authenticated-orcid":false,"given":"Marcos","family":"Molina\u2010Fernandez","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS) University of Granada  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0715-8620","authenticated-orcid":false,"given":"Manuel","family":"Dote\u2010Montero","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS) University of Granada  Granada Spain"},{"name":"Obesity and Diabetes Clinical Research Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases National Institutes of Health  Phoenix Arizona USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8312-1438","authenticated-orcid":false,"given":"Jordi","family":"Merino","sequence":"additional","affiliation":[{"name":"Novo Nordisk Foundation Center for Basic Metabolic Research University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9645-3260","authenticated-orcid":false,"given":"Manuel","family":"Mu\u00f1oz\u2010Torres","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Biosanitaria de Granada (ibs. GRANADA)  Granada Spain"},{"name":"Endocrinology and Nutrition Unit University Hospital San Cecilio Clinic  Granada Spain"},{"name":"Department of Medicine University of Granada  Granada Spain"},{"name":"CIBER on Frailty and Healthy Aging (CIBERFES) Carlos III Health Institute  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4334-3287","authenticated-orcid":false,"given":"Idoia","family":"Labayen","sequence":"additional","affiliation":[{"name":"ELIKOS Research Group, Institute for Sustainability &amp; Food Chain Innovation, Department of Health Sciences Public University of Navarre  Pamplona Spain"},{"name":"Navarra Institute for Health Research (IdiSNA)  Pamplona Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red: Fisiopatolog\u00eda de la Obesidad y Nutrici\u00f3n (CIBEROBN) Instituto de Salud Carlos III  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7548-7138","authenticated-orcid":false,"given":"Jonatan R.","family":"Ruiz","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS) University of Granada  Granada Spain"},{"name":"Instituto de Investigaci\u00f3n Biosanitaria de Granada (ibs. GRANADA)  Granada Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red: Fisiopatolog\u00eda de la Obesidad y Nutrici\u00f3n (CIBEROBN) Instituto de Salud Carlos III  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,19]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41569\u2010023\u201000847\u20105"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.adp9358"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/DOM.16104"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2022.01.038"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591\u2010024\u201003155\u20108"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/HCQ.0000000000000139"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/NRENDO.2009.23"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41574\u2010018\u20100122\u20101"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.SMRV.2023.101788"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/SLEEPADVANCES\/ZPAE095"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/BMJOPEN\u20102022\u2010062239"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.2337\/DB09\u20100699"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/SLEEP\/ZSX014"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/OBY.24162"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/JAMANETWORKOPEN.2025.0114"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2023.1227372"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdi.70075"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.12355"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/S00125\u2010021\u201005608\u2010Y\/TABLES\/2"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1126\/SCIENCE.AAH4967"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1371\/JOURNAL.PONE.0142533"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2015.09.005"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213\u20108587(22)00319\u20109"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591\u2010024\u201003375\u2010y"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102023\u2010078472"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2023.09.014"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1123\/jmpb.2018\u20100063"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/S41598\u2010018\u201031266\u2010Z"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/SLEEP\/ZSAB254"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/S41598\u2010017\u201003171\u20104"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0191883"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0000000000000289"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/OBY.24063"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.5935\/1984\u20100063.20200084"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc10\u20101962"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.2337\/DC19\u20100298"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.14930"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2016.03.005"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2024.101926"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/S11892\u2010020\u201001324\u2010W"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.XCRM.2023.101100"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2018.02.010"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.TEM.2019.11.011"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.3390\/s16122093"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/dme.13584"}],"container-title":["Diabetes, Obesity and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dom-pubs.pericles-prod.literatumonline.com\/doi\/pdf\/10.1111\/dom.70675","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dom-pubs.pericles-prod.literatumonline.com\/doi\/full-xml\/10.1111\/dom.70675","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dom-pubs.pericles-prod.literatumonline.com\/doi\/pdf\/10.1111\/dom.70675","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T03:06:19Z","timestamp":1780455979000},"score":1,"resource":{"primary":{"URL":"https:\/\/dom-pubs.pericles-prod.literatumonline.com\/doi\/10.1111\/dom.70675"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,19]]},"references-count":45,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1111\/dom.70675"],"URL":"https:\/\/doi.org\/10.1111\/dom.70675","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/DOM.70675\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70675\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70675\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70675\/v2\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70675\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70675\/v3\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70675\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70675\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70675\/v1\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70675\/v1\/review4","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70675\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70675\/v2\/decision1","asserted-by":"object"}]},"ISSN":["1462-8902","1463-1326"],"issn-type":[{"value":"1462-8902","type":"print"},{"value":"1463-1326","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,19]]},"assertion":[{"value":"2026-01-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}