{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:56:52Z","timestamp":1786121812932,"version":"build-2736575974"},"reference-count":34,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T00:00:00Z","timestamp":1776988800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T00:00:00Z","timestamp":1776988800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To characterise continuous glucose monitoring (CGM)\u2010derived glycaemic patterns across the dialysis cycle and to assess associations between CGM metrics, interdialytic weight gain (IDWG) as a marker of volume status, and intradialytic adverse events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>In this prospective observational study, adults with insulin\u2010treated diabetes receiving maintenance haemodialysis underwent 2\u2010week CGM assessment. CGM metrics were summarised for pre\u2010dialytic, intradialytic and post\u2010dialytic periods. Multivariable regression assessed associations between CGM metrics, HbA1c, IDWG, intradialytic hypoglycaemia and intradialytic hypotension (IDH).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In total, 40 participants (age 56.6\u2009\u00b1\u200914.7\u2009years, 60% type 2 diabetes, diabetes duration 24.5\u2009\u00b1\u20099.9\u2009years, HbA1c 68\u2009\u00b1\u200919\u2009mmol\/mol [8.4%\u2009\u00b1\u20091.7%]) contributed 11\u2009096 CGM glucose readings and 246 haemodialysis sessions. Time in range (TIR, 3.9\u201310.0\u2009mmol\/L) increased from pre\u2010dialytic to intradialytic period (36.1% vs. 60.9%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and decreased post\u2010dialysis to 17.8% (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Mean glucose reduced during dialysis by 32% (from 11.1\u2009\u00b1\u20093.5\u2009mmol\/L at initiation to an intradialytic nadir of 7.6\u2009\u00b1\u20092.2\u2009mmol\/L at 125\u2009min). Lower baseline 14\u2010day TIR, but not HbA1c or glucose level at dialysis initiation, was independently associated with higher IDWG, which was an independent risk factor for recurrent IDH. Intradialytic hypoglycaemia (20.0% of participants) was associated with higher baseline 14\u2010day time below range (&lt;\u20093.9\u2009mmol\/L) (OR 2.42 per 1% increase,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.049).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>CGM identifies dialysis\u2010specific glycaemic patterns and clinically relevant associations with IDWG and intradialytic hypoglycaemia that extend beyond HbA1c. These findings support broader evaluation of CGM in haemodialysis populations with diabetes to inform future CGM\u2010guided strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.70808","type":"journal-article","created":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T09:00:04Z","timestamp":1777021204000},"page":"6062-6072","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Continuous Glucose Monitoring in Adults With Diabetes Receiving Haemodialysis: Identifying Dialysis\u2010Specific Glycaemic Patterns and Associations With Volume Status and Intradialytic Hypoglycaemia"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1713-3064","authenticated-orcid":false,"given":"Alexandros L.","family":"Liarakos","sequence":"first","affiliation":[{"name":"Department of Diabetes and Endocrinology University Hospitals of Derby and Burton NHS Foundation Trust, Royal Derby Hospital  Derby UK"},{"name":"School of Medicine, Faculty of Medicine and Health Sciences University of Nottingham  Nottingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashveer","family":"Randhay","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine University Hospitals of Derby and Burton NHS Foundation Trust, Royal Derby Hospital  Derby UK"},{"name":"Centre for Kidney Research and Innovation, School of Medicine University of Nottingham  Nottingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lalantha","family":"Leelarathna","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Metabolism, Digestion and Reproduction Imperial College London  London UK"},{"name":"Department of Diabetes, Imperial College Healthcare NHS Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas S. J.","family":"Crabtree","sequence":"additional","affiliation":[{"name":"Department of Diabetes and Endocrinology University Hospitals of Derby and Burton NHS Foundation Trust, Royal Derby Hospital  Derby UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brett","family":"Doleman","sequence":"additional","affiliation":[{"name":"School of Medicine, Faculty of Medicine and Health Sciences University of Nottingham  Nottingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Tarek","family":"Eldehni","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine University Hospitals of Derby and Burton NHS Foundation Trust, Royal Derby Hospital  Derby UK"},{"name":"Centre for Kidney Research and Innovation, School of Medicine University of Nottingham  Nottingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0351-8326","authenticated-orcid":false,"given":"Nicholas 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