{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T00:14:48Z","timestamp":1789172088809,"version":"build-2803163510"},"reference-count":40,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T00:00:00Z","timestamp":1779062400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T00:00:00Z","timestamp":1779062400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2026,8]]},"abstract":"ABSTRACT<\/jats:title>\n \n Aims<\/jats:title>\n Despite its rising prevalence, older adults with Type 1 diabetes remain poorly characterised. This study aimed to characterise those over 60\u2009years and quantify independent predictors of glycaemic control and complications.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods<\/jats:title>\n We performed a multicentre analysis using real\u2010world data from the China Diabetes Type 1 Study (CD1S), including 69 centres across China between 2016 and 2021. Patients were stratified into three age groups (\u2265\u200960, 18\u201359 and <\u200918\u2009years) for assessment of clinical characteristics and complications. Multiple regression examined associations of clinical features with HbA1c and complications. Variable importance was interpreted using SHAP values derived from a random forest model.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n We enrolled 9637 patients with Type 1 diabetes. Compared with young adults, older adults with Type 1 diabetes were less likely to achieve target HbA1c (7.2% vs. 10.2%,\n p<\/jats:italic>\n \u2009<\u20090.05) and had a substantially higher burden of chronic complications, with 81.0% of older adults having at least one complication. Longer duration, higher BMI and higher gross domestic product (GDP) were significantly associated with lower HbA1c (all\n p<\/jats:italic>\n \u2009<\u20090.05). Higher GDP was linked to reduced rates of diabetic retinopathy (19.7%), nephropathy (13.6%) and peripheral neuropathy (46.9%), yet a higher proportion of peripheral vasculopathy (41.8%) was observed compared with middle\u2010 and low\u2010GDP regions.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Older adults with Type 1 diabetes exhibit a unique clinical profile of poor glycaemic control and a high burden of complications, influenced by regional GDP disparities. This underscores the critical need to integrate socioeconomic factors into personalised care strategies to advance health equity.<\/jats:p>\n \n Registration number:<\/jats:bold>\n NCT05498974.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/dom.70833","type":"journal-article","created":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T06:10:57Z","timestamp":1779171057000},"page":"6850-6860","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Health Inequities in Older Adults With Type 1 Diabetes: A Nationwide Registry Analysis of Sociodemographic and Clinical Profiles for Glycaemic Control and Complications"],"prefix":"10.1111","volume":"28","author":[{"given":"Chao","family":"Deng","sequence":"first","affiliation":[{"name":"National Clinical Research Center for Endocrine and Metabolic Diseases, Key Laboratory of Diabetes Immunology, Ministry of Education, and Department of Metabolism and Endocrinology The Second Xiangya Hospital of Central South University Changsha Hunan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenqi","family":"Fan","sequence":"additional","affiliation":[{"name":"National Clinical Research Center for Endocrine and Metabolic Diseases, Key Laboratory of Diabetes Immunology, Ministry of Education, and Department of Metabolism and Endocrinology The Second Xiangya Hospital of Central South University Changsha Hunan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuting","family":"Xie","sequence":"additional","affiliation":[{"name":"National Clinical Research Center for Endocrine and Metabolic Diseases, Key Laboratory of Diabetes Immunology, Ministry of Education, and Department of Metabolism and Endocrinology The Second Xiangya Hospital of Central South University Changsha Hunan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohan","family":"Tang","sequence":"additional","affiliation":[{"name":"National Clinical Research Center for Endocrine and Metabolic Diseases, Key Laboratory of Diabetes Immunology, Ministry of Education, and Department of Metabolism and Endocrinology The Second Xiangya Hospital of Central South University Changsha Hunan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongwei","family":"Jiang","sequence":"additional","affiliation":[{"name":"Henan Key Laboratory of Rare Diseases, Endocrinology and Metabolism Center, the First Affiliated Hospital College of Clinical Medicine of Henan University of Science and Technology Luoyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohong","family":"Niu","sequence":"additional","affiliation":[{"name":"Department of Endocrinology Changzhi Medical College Affiliated Heji Hospital Changzhi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dewen","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Endocrinology Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen Clinical Research Center for Metabolic Diseases, Shenzhen Center for Diabetes Control and Prevention Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heng","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism First People's Hospital of Yunnan Province (The Affiliated Hospital of Kunming University of Science and Technology) Kunming China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyu","family":"Kuang","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Harbin Medical University Harbin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0630-0974","authenticated-orcid":false,"given":"Limin","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Endocrinology Gansu Provincial Hospital Lanzhou 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