{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T00:14:40Z","timestamp":1789172080050,"version":"build-2803163510"},"reference-count":30,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T00:00:00Z","timestamp":1778371200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T00:00:00Z","timestamp":1778371200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100018732","name":"Vissing Fonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100018732","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010809","name":"Jascha Fonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100024075","name":"Region Syddanmark","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100024075","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015223","name":"Danish Diabetes and Endocrine Academy","doi-asserted-by":"publisher","award":["NFF 17SA0031406"],"award-info":[{"award-number":["NFF 17SA0031406"]}],"id":[{"id":"10.13039\/100015223","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The risk of delivering a small\u2010for\u2010gestational\u2010age (SGA) neonate is increased after Roux\u2010en\u2010Y gastric bypass (RYGB). Because glucose is the foetus's primary energy source and postprandial hypoglycemia is common after RYGB, the Bariatric surgery And consequences for Mother and Baby In pregnancy (BAMBI) study examined associations between trimester specific maternal hypoglycemia and offspring birthweight as well as other perinatal outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Twenty\u2010three pregnant women with RYGB and 23 BMI\u2010 and parity\u2010matched controls were followed prospectively with continuous glucose monitoring (CGM) and foetal ultrasounds in each trimester. At birth, neonatal anthropometric measures, including skinfold measurements, were obtained. Exposure to hypoglycaemia was defined as spending &gt;\u20094% of the time with interstitial glucose &lt;\u20093.5\u2009mmol\/L. Multivariable regression was used to examine associations between exposure to hypoglycaemia in each trimester and birthweight, adjusting for maternal age, parity, pre\u2010pregnancy body mass index, gestational weight gain and surgery\u2010to\u2010conception interval.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Baseline characteristics were similar regardless of exposure to hypoglycemia. Spending &gt;\u20094% of the time in hypoglycemia during the second or third trimester was associated with a 550\u2009g lower birthweight (95% CI [\u22121031\u2013\u221269],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03), while no such association was observed for the first trimester. Infants exposed to second\/third trimester hypoglycemia had lower abdominal circumference percentiles (20th vs. 55th,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01) and lighter placentas (580\u2009g vs. 705\u2009g,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Increased maternal hypoglycemia in the second or third trimester of pregnancy post\u2010RYGB appears to be associated with reduced foetal growth. Optimising glucose levels through CGM may help prevent SGA births in this population.<\/jats:p>\n                    <jats:p>\n                      <jats:bold>Trial Registration:<\/jats:bold>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/ClinicalTrials.gov\">ClinicalTrials.gov<\/jats:ext-link>\n                      identifier: NCT03713060\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.70852","type":"journal-article","created":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T03:41:02Z","timestamp":1778470862000},"page":"6649-6660","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Maternal Hypoglycemia and Reduced Foetal Growth in Pregnancies Following Roux\u2010en\u2010Y Gastric Bypass: A Prospective Cohort Study"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1419-0223","authenticated-orcid":false,"given":"Louise L.","family":"Stentebjerg","sequence":"first","affiliation":[{"name":"Steno Diabetes Center Odense Odense University Hospital  Odense Denmark"},{"name":"Department of Clinical Research University of Southern Denmark  Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8964-9564","authenticated-orcid":false,"given":"Lene R.","family":"Madsen","sequence":"additional","affiliation":[{"name":"Steno Diabetes Center Aarhus Aarhus University Hospital  Aarhus Denmark"},{"name":"Danish Diabetes &amp; Endocrine Academy Odense University Hospital  Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4255-5544","authenticated-orcid":false,"given":"Ren\u00e9 K.","family":"St\u00f8ving","sequence":"additional","affiliation":[{"name":"Department of Clinical Research University of Southern Denmark  Odense Denmark"},{"name":"Department of Endocrinology Odense University Hospital  Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2997-2228","authenticated-orcid":false,"given":"Lise Lotte T.","family":"Andersen","sequence":"additional","affiliation":[{"name":"Department of Clinical Research University of Southern Denmark  Odense Denmark"},{"name":"Department of Gynecology and Obstetrics Odense University Hospital  Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4285-5459","authenticated-orcid":false,"given":"Claus B.","family":"Juhl","sequence":"additional","affiliation":[{"name":"Department of Endocrinology University Hospital of Southern Denmark  Esbjerg Denmark"},{"name":"Department of Regional Health Research University of Southern Denmark  Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5084-6053","authenticated-orcid":false,"given":"Christina A.","family":"Vinter","sequence":"additional","affiliation":[{"name":"Steno Diabetes Center Odense Odense University Hospital  Odense Denmark"},{"name":"Department of Gynecology and Obstetrics Odense University Hospital  Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3298-9824","authenticated-orcid":false,"given":"Dorte M.","family":"Jensen","sequence":"additional","affiliation":[{"name":"Steno Diabetes Center Odense Odense University Hospital  Odense Denmark"},{"name":"Department of Gynecology and Obstetrics Odense University Hospital  Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,10]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2007.01809.x"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-023-05937-0"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2018.02.003"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002866"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ogx.0000466883.05862.27"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.soard.2020.12.009"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-020-05219-3"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/a-0651-0424"},{"key":"e_1_2_11_10_1","volume-title":"The 6th IFSO 2021 Registry Report","author":"Brown A. 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