{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T00:13:48Z","timestamp":1789172028306,"version":"build-2803163510"},"reference-count":47,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T00:00:00Z","timestamp":1780444800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T00:00:00Z","timestamp":1780444800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100009228","name":"Region \u00d6rebro l\u00e4n","doi-asserted-by":"publisher","award":["OLL\u2010886441"],"award-info":[{"award-number":["OLL\u2010886441"]}],"id":[{"id":"10.13039\/501100009228","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009228","name":"Region \u00d6rebro l\u00e4n","doi-asserted-by":"publisher","award":["OLL\u2010935216"],"award-info":[{"award-number":["OLL\u2010935216"]}],"id":[{"id":"10.13039\/501100009228","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009228","name":"Region \u00d6rebro l\u00e4n","doi-asserted-by":"publisher","award":["OLL\u2010939125"],"award-info":[{"award-number":["OLL\u2010939125"]}],"id":[{"id":"10.13039\/501100009228","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009228","name":"Region \u00d6rebro l\u00e4n","doi-asserted-by":"publisher","award":["OLL\u2010964732"],"award-info":[{"award-number":["OLL\u2010964732"]}],"id":[{"id":"10.13039\/501100009228","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009228","name":"Region \u00d6rebro l\u00e4n","doi-asserted-by":"publisher","award":["OLL\u2010970429"],"award-info":[{"award-number":["OLL\u2010970429"]}],"id":[{"id":"10.13039\/501100009228","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009228","name":"Region \u00d6rebro l\u00e4n","doi-asserted-by":"publisher","award":["OLL\u2010983440"],"award-info":[{"award-number":["OLL\u2010983440"]}],"id":[{"id":"10.13039\/501100009228","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100023670","name":"Nyckelfonden","doi-asserted-by":"publisher","award":["OLL\u2010886841"],"award-info":[{"award-number":["OLL\u2010886841"]}],"id":[{"id":"10.13039\/501100023670","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100023670","name":"Nyckelfonden","doi-asserted-by":"publisher","award":["OLL\u2010935201"],"award-info":[{"award-number":["OLL\u2010935201"]}],"id":[{"id":"10.13039\/501100023670","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100023670","name":"Nyckelfonden","doi-asserted-by":"publisher","award":["OLL\u2010973006"],"award-info":[{"award-number":["OLL\u2010973006"]}],"id":[{"id":"10.13039\/501100023670","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Low\u2010energy diet (LED) plus cognitive\u2010behavioural therapy (CBT) produces substantial short\u2010term weight loss in obesity, but long\u2010term maintenance remains difficult. We evaluated whether adding intragastric balloon (IGB) treatment to group\u2010based CBT improves weight maintenance after initial weight loss using LED.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      In this open\u2010label randomized controlled trial, adults aged 30\u201365\u2009years with BMI 32.5\u201345\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      underwent a 6\u2010month run\u2010in period combining LED and group\u2010based CBT and were subsequently randomized to CBT and 1\u2010year IGB or CBT alone. The primary endpoint was weight change in percent between randomization (6\u2009months from enrollment) and 18\u2009months (from enrollment), compared to total body weight (TBW) at enrollment. Secondary outcomes included the proportion of participants achieving weight loss thresholds, metabolic parameters and health\u2010related quality of life (HRQoL).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 126 enrolled (mean 43.7\u2009years; BMI 38.0\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ), 107 were randomized 6\u2009months after enrollment (IGB\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200951; CBT\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200956) and lost \u221218.7% (SE: 0.64) of TBW. At 18\u2009months, the mean weight change from randomization was 5.2% with IGB versus 10.1% with CBT (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). A significantly greater proportion of IGB recipients achieved \u2265\u20095% (84.3% vs. 63.6%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.021) and \u2265\u200910% (70.6% vs. 45.5%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.013) weight loss after 18\u2009months, compared to the CBT group. Improvements in metabolic parameters and HRQoL showed no between\u2010group differences.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>As an adjunct to group\u2010based CBT and after LED\u2010induced weight loss, IGB treatment provided a modest advantage in weight maintenance for up to 18\u2009months, although safety concerns remain and long\u2010term studies are warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.70865","type":"journal-article","created":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T02:01:42Z","timestamp":1780538502000},"page":"7300-7311","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Intragastric Balloon Treatment Enhances Weight Maintenance Adjunct to Low\u2010Energy Diet and Group\u2010Based Cognitive Behavioural Therapy: A Randomized Controlled Trial"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9963-979X","authenticated-orcid":false,"given":"Marije","family":"Galavazi","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine and Health \u00d6rebro University  \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qays","family":"Shahed","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine and Health \u00d6rebro University  \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9736-8228","authenticated-orcid":false,"given":"Hugo","family":"Hesser","sequence":"additional","affiliation":[{"name":"School of Behavioural, Social and Legal Sciences, Center for Health and Medical Psychology \u00d6rebro University  \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Cao","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology and Biostatistics, School of Medical Sciences, Faculty of Medicine and Health \u00d6rebro University  \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6864-4679","authenticated-orcid":false,"given":"Stefan","family":"Jansson","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health University Health Care Research Center, \u00d6rebro University  \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6348-2308","authenticated-orcid":false,"given":"Michiel","family":"van Nieuwenhoven","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health University Health Care Research Center, \u00d6rebro University  \u00d6rebro Sweden"},{"name":"Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine and Health \u00d6rebro University  \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1025-1682","authenticated-orcid":false,"given":"Johan","family":"Jendle","sequence":"additional","affiliation":[{"name":"School of Medical Sciences \u00d6rebro University  \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,3]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(22)00033-X"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000442721"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanepe.2024.101034"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2521-4"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)30175-1"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)02750-2"},{"key":"e_1_2_11_8_1","unstructured":"\u201cThe National Public Health Survey National and Regional Results \u201d(2024) https:\/\/www.folkhalsomyndigheten.se\/vara\u2010amnesomraden\/overvikt\u2010och\u2010obesitas\/overvikt\u2010och\u2010obesitas\u2010i\u2010befolkningen\/."},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(16)30162-0"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12113"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42255-023-00864-1"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41574-023-00887-4"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.13003"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2010.334"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa012512"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.14200"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v29.i40.5526"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-40141-5"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2020.103654"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.20662"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12816"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1159\/000515381"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/osp4.464"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2021.03.003"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-017-2636-3"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu14163450"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-023-10390-6"},{"key":"e_1_2_11_28_1","unstructured":"Ministers NCo \u201cNordic Nutrition Recommendations 2012: Nordic Council of Ministers \u201daccessed 12 February 2026 https:\/\/www.norden.org\/en\/publication\/nordic\u2010nutrition\u2010recommendations\u20102012."},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41687-018-0030-0"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12955-022-01992-0"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/9780470316696"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/cob.12030"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1381\/0960892053723411"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-021-05729-8"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-022-06398-x"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-024-07524-7"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-024-07128-1"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.4253\/wjge.v17.i10.109031"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-020-04985-4"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(15)00291-0"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-022-05567-8"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc21-1805"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.122.009348"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/osp4.70010"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-024-04952-z"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2020-039295"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13679-021-00453-x"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm14217602"}],"container-title":["Diabetes, Obesity and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dom-pubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dom.70865","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dom-pubs.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/dom.70865","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dom-pubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dom.70865","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T23:44:34Z","timestamp":1789170274000},"score":1,"resource":{"primary":{"URL":"https:\/\/dom-pubs.onlinelibrary.wiley.com\/doi\/10.1111\/dom.70865"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,3]]},"references-count":47,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1111\/dom.70865"],"URL":"https:\/\/doi.org\/10.1111\/dom.70865","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/DOM.70865\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70865\/v1\/review5","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70865\/v1\/review4","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70865\/v1\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70865\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70865\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70865\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70865\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70865\/v2\/response1","asserted-by":"object"}]},"ISSN":["1462-8902","1463-1326"],"issn-type":[{"value":"1462-8902","type":"print"},{"value":"1463-1326","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,3]]},"assertion":[{"value":"2026-02-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}