{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T08:09:08Z","timestamp":1792829348488,"version":"4.5.0"},"reference-count":56,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T00:00:00Z","timestamp":1781222400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T00:00:00Z","timestamp":1781222400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001866","name":"Fonds National de la Recherche Luxembourg","doi-asserted-by":"publisher","award":["PRIDE21\/16749720"],"award-info":[{"award-number":["PRIDE21\/16749720"]}],"id":[{"id":"10.13039\/501100001866","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Diabetes distress (DD) is common and evolves heterogeneously over time. We aimed to estimate minimal clinically important differences (MCID) for the Problem Areas in Diabetes (PAID) scale and its sub\u2010dimensions and to identify predictors of worsening over 1 year in people with type 1 diabetes (PwT1D).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>MCIDs for PAID total and sub\u2010dimension scores were derived using the standard error of measurement approach. One\u2010year DD worsening, stability and improvement were defined using the \u00b11 MCID threshold. We analysed changes in DD using data from the SFDT1 cohort. Logistic regression models identified predictors of worsening for PAID total and sub\u2010dimensions, adjusting for baseline DD, age, sex and social vulnerability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We analysed data from 2457 adults with type 1 diabetes (51.6% female, 41.3\u2009years old (SD 14.0), 23.7\u2009years diabetes duration (SD 14.0)). The MCID for PAID total was 5.0 points, with sub\u2010scale MCIDs ranging from 8.5 (emotional distress) to 14.3 points (management distress). Over 1 year, 42% experienced clinically meaningful worsening of total DD, 30% improved and 28% remained stable. Worsening of total PAID was associated with social vulnerability, HbA1c increase and treatment burden. Distress trajectories varied across sub\u2010dimensions, with emotional distress and burnout most frequently worsening (34% each); initiation of automated insulin delivery was solely associated with lower odds of worsening on the burnout dimension.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study provides MCID values for the PAID scale and its sub\u2010dimensions. The high temporal variability observed suggests a need for regular monitoring and clinically informed assessment of DD in PwT1D.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.70932","type":"journal-article","created":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T09:36:48Z","timestamp":1781257008000},"page":"7905-7915","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["What Is a Clinically Meaningful Change in Diabetes Distress? Findings for Diabetes Care and Research From the\n                    <scp>SFDT1<\/scp>\n                    Cohort"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-4763-1026","authenticated-orcid":false,"given":"Dulce","family":"Canha","sequence":"first","affiliation":[{"name":"Deep Digital Phenotyping Research Unit, Department of Precision Health Luxembourg Institute of Health  Strassen Luxembourg"},{"name":"Faculty of Science, Technology and Medicine University of Luxembourg  Esch\u2010sur\u2010Alzette Luxembourg"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7991-0741","authenticated-orcid":false,"given":"Jean\u2010Pierre","family":"Riveline","sequence":"additional","affiliation":[{"name":"Institut Necker Enfants Malades IMMEDIAB Laboratory  Paris France"},{"name":"Centre Universitaire du Diab\u00e8te et de ses Complications APHP, H\u00f4pital Lariboisi\u00e8re  Paris 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CHU Grenoble Alpes  Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8731-7355","authenticated-orcid":false,"given":"Micha\u00ebl","family":"Joubert","sequence":"additional","affiliation":[{"name":"Diabetes Care Unit Caen\u2010University Hospital, Unicaen  Caen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3056-3640","authenticated-orcid":false,"given":"Fawaz","family":"Alzaid","sequence":"additional","affiliation":[{"name":"Institut Necker Enfants Malades IMMEDIAB Laboratory  Paris France"},{"name":"Dasman Diabetes Institute  Kuwait City Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8785-3385","authenticated-orcid":false,"given":"Emmanuel","family":"Cosson","sequence":"additional","affiliation":[{"name":"Department of Endocrinology\u2010Diabetology\u2010Nutrition AP\u2010HP, Avicenne Hospital, Paris 13 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