{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T18:35:59Z","timestamp":1793126159816,"version":"4.5.0"},"reference-count":38,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T00:00:00Z","timestamp":1780876800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T00:00:00Z","timestamp":1780876800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To assess key patient\u2010reported outcomes (PROs) in individuals with insulin\u2010treated diabetes receiving haemodialysis and examine associations between continuous glucose monitoring (CGM) metrics, HbA1c and PROs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>In this cross\u2010sectional study, adults with insulin\u2010treated diabetes receiving haemodialysis and using CGM were recruited. PROs included glucose monitoring satisfaction (GMSS), diabetes distress (DDS\u201017, PAID), kidney failure\u2013related symptom burden (IPOS\u2010Renal), thirst (Dialysis Thirst Inventory) and hypoglycaemia awareness (Gold score). CGM metrics were defined according to international consensus recommendations. Multivariable regression analyses examined associations between CGM metrics, HbA1c and PROs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Forty participants were included. CGM satisfaction was high (median GMSS 4.5 [IQR 3.9\u20134.7]) with low CGM use\u2010related burden. Overall diabetes distress was low (median DDS\u201017 1.7 [1.3\u20132.2]), although emotional burden was frequently reported. Kidney failure\u2013related symptom burden was high. Thirst was common, with 65% of participants reporting problematic thirst. CGM metrics were consistently associated with multiple PROs, whereas HbA1c showed fewer associations. Higher time in range (3.9\u201310.0\u2009mmol\/L) was associated with greater CGM satisfaction (total GMSS score; unstandardised coefficient [\n                      <jats:italic>B<\/jats:italic>\n                      ] 0.009,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.044), lower regimen\u2010related distress (\n                      <jats:italic>B<\/jats:italic>\n                      \u2009\u2212\u20090.012,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.040) and lower odds of problematic thirst (OR 0.79 per 5% increase,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.021) and intradialytic thirst (OR 0.77,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.017). Higher HbA1c was associated with increased odds of problematic thirst (OR 2.30 per 11\u2009mmol\/mol increase,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.014) and nocturnal thirst (OR 1.66,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.040). Most had intact hypoglycaemia awareness (35\/40, 87.5%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In individuals with insulin\u2010treated diabetes receiving haemodialysis, CGM metrics were consistently associated with patient\u2010reported experience, particularly thirst, and may provide clinically relevant insights beyond HbA1c. Further studies should evaluate whether optimising glycaemic exposure translates into improved patient\u2010reported outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.70954","type":"journal-article","created":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T03:19:27Z","timestamp":1780975167000},"page":"7536-7545","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Associations Between Patient\u2010Reported Outcomes and Glycaemic Exposure in Continuous Glucose Monitoring Users With Insulin\u2010Treated Diabetes Receiving Haemodialysis"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1713-3064","authenticated-orcid":false,"given":"Alexandros L.","family":"Liarakos","sequence":"first","affiliation":[{"name":"Department of Diabetes and Endocrinology University Hospitals of Derby and Burton NHS Foundation Trust, Royal Derby Hospital  Derby UK"},{"name":"School of Medicine, Faculty of Medicine and Health Sciences University of Nottingham  Nottingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashveer","family":"Randhay","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine University Hospitals of Derby and Burton NHS Foundation Trust, Royal Derby Hospital  Derby UK"},{"name":"Centre for Kidney Research and Innovation, School of Medicine University of Nottingham  Nottingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lalantha","family":"Leelarathna","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Metabolism, Digestion and Reproduction Imperial College London  London UK"},{"name":"Department of Diabetes Imperial College Healthcare NHS Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas S. 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