{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T18:36:04Z","timestamp":1793126164100,"version":"4.5.0"},"reference-count":23,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T00:00:00Z","timestamp":1780876800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T00:00:00Z","timestamp":1780876800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["R01DK119450"],"award-info":[{"award-number":["R01DK119450"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011946","name":"Abbott Diabetes Care","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011946","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2026,8]]},"abstract":"ABSTRACT<\/jats:title>\n \n Aim<\/jats:title>\n Youth\u2010onset type 2 diabetes and obesity are rising public health burdens. While newer type 2 diabetes medications lower HbA1c, their impact on paediatric weight loss is inconsistent. In contrast, bariatric surgery improves glycemia and weight in youth and adults, though glycemia post\u2010vertical sleeve gastrectomy (VSG), now the predominant bariatric surgery in youth, remains unstudied in youth\u2010onset type 2 diabetes. We aimed to assess immediate post\u2010VSG glycemic patterns using continuous glucose monitoring (CGM) in adolescents with type 2 diabetes.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods<\/jats:title>\n \n In the Surgical or Medical Treatment for Paediatric Type 2 Diabetes (ST\n 2<\/jats:sub>\n OMP) study, 73 adolescents with type 2 diabetes underwent 14\u2009days of CGM monitoring: 33 participants beginning in the 1\u20132\u2009days post\u2010VSG (mean age 17.6\u2009years, 67% female, HbA1c 7.2%, BMI 50.0\u2009kg\/m\n 2<\/jats:sup>\n ) and 40 participants receiving advanced medical therapy (AMT) (mean age 16.9\u2009years, 53% female, HbA1c 7.8%, BMI 42.2\u2009kg\/m\n 2<\/jats:sup>\n ). CGM analyses included glucose management indicator (GMI), time in range, coefficient of variability, standard deviation, mean amplitude glycemic excursion, percent >\u2009140, 180, and 200, percent <\u200970 and 60\u2009mg\/dL, 7\u2009a.m., and midnight\u20106\u2009a.m.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Mean glucose was 84.3\u2009\u00b1\u200923.4 in the post\u2010VSG group versus 149.8\u2009\u00b1\u200978.8\u2009mg\/dL in the AMT group (\n p<\/jats:italic>\n \u2009<\u20090.001). Mean CGM GMI was normal (5.3%, 34\u2009mmol\/mol) post\u2010VSG versus in the diabetes range (6.9%, 52\u2009nmol\/mol) with AMT (\n p<\/jats:italic>\n \u2009<\u20090.001). VSG participants spent more time\u2009<\u200970\u2009mg\/dL, 55\u2009mg\/dL, and 45\u2009mg\/dL (all\n p<\/jats:italic>\n \u2009<\u20090.01). After BMI adjustment, preoperative HbA1c predicted postoperative glucose metrics.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Adolescents with type 2 diabetes experience early glycemic normalization post\u2010VSG, even before major weight loss.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/dom.70961","type":"journal-article","created":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T01:18:28Z","timestamp":1780967908000},"page":"7555-7561","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Glycemic Normalization Immediately Following Vertical Sleeve Gastrectomy in Adolescents With Type 2 Diabetes From the\n \n ST\n 2<\/sub>\n OMP\n <\/scp>\n Study"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1212-9082","authenticated-orcid":false,"given":"Natalie","family":"Segev","sequence":"first","affiliation":[{"name":"Division of Diabetes and Endocrinology Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA"},{"name":"Department of Pediatrics University of Cincinnati College of Medicine Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0477-3356","authenticated-orcid":false,"given":"Kristen J.","family":"Nadeau","sequence":"additional","affiliation":[{"name":"Section of Pediatric Endocrinology University of Colorado Anschutz Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"Kelsey","sequence":"additional","affiliation":[{"name":"Section of Pediatric Endocrinology University of Colorado Anschutz Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa R.","family":"Schaaf","sequence":"additional","affiliation":[{"name":"Division of Diabetes and Endocrinology Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Baumgartner","sequence":"additional","affiliation":[{"name":"Section of Pediatric Endocrinology University of Colorado Anschutz Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allen","family":"Riegler","sequence":"additional","affiliation":[{"name":"Division of Diabetes and Endocrinology Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"Wiitala","sequence":"additional","affiliation":[{"name":"Section of Pediatric Endocrinology University of Colorado Anschutz Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd M.","family":"Jenkins","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Cincinnati College of Medicine Cincinnati Ohio USA"},{"name":"Division of Biostatistics and Epidemiology Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stavra A.","family":"Xanthakos","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Cincinnati College of Medicine Cincinnati Ohio USA"},{"name":"Department of Gastroenterology, Hepatology, and Nutrition Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Helmrath","sequence":"additional","affiliation":[{"name":"Division of Pediatric General and Thoracic Surgery Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA"},{"name":"Department of Surgery University of Cincinnati College of Medicine Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas H.","family":"Inge","sequence":"additional","affiliation":[{"name":"Department of Surgery Northwestern University Feinberg School of Medicine Chicago Illinois USA"},{"name":"Department of Surgery Ann & Robert H. Lurie Children's Hospital of Chicago Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy Sanghavi","family":"Shah","sequence":"additional","affiliation":[{"name":"Division of Diabetes and Endocrinology Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA"},{"name":"Department of Pediatrics University of Cincinnati College of Medicine Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,8]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc18\u20100243"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.2337\/db19\u20100299"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc25\u2010S014"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2204601"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2022\u2010060640"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc25\u2010S008"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1700459"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2014.2440"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1600869"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.soard.2018.04.002"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2017.5763"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmc2404054"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/s2213\u20108587(13)70218\u20103"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102020\u2010047766"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.10.5.622"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0248560"},{"key":"e_1_2_11_18_1","unstructured":"\u201cR: A Language and Environment for Statistical Computing \u201dhttps:\/\/www.R\u2010project.org\/."},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc09\u20101971"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/19322968221099879"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.2337\/db12\u20101762"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc26\u2010S016"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213\u20108587(20)30381\u20108"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.2018\u201000183"}],"container-title":["Diabetes, Obesity and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dom-pubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dom.70961","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dom-pubs.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/dom.70961","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dom-pubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dom.70961","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T18:16:41Z","timestamp":1793125001000},"score":1,"resource":{"primary":{"URL":"https:\/\/dom-pubs.onlinelibrary.wiley.com\/doi\/10.1111\/dom.70961"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,8]]},"references-count":23,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1111\/dom.70961"],"URL":"https:\/\/doi.org\/10.1111\/dom.70961","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/DOM.70961\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70961\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70961\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70961\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70961\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.70961\/v1\/review3","asserted-by":"object"}]},"ISSN":["1462-8902","1463-1326"],"issn-type":[{"value":"1462-8902","type":"print"},{"value":"1463-1326","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,8]]},"assertion":[{"value":"2026-04-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}