{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T14:09:01Z","timestamp":1789394941741,"version":"build-2803163510"},"reference-count":29,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000361","name":"Diabetes UK","doi-asserted-by":"publisher","award":["22\/0006478"],"award-info":[{"award-number":["22\/0006478"]}],"id":[{"id":"10.13039\/501100000361","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To compare postpartum trajectories in body weight and cardiometabolic biomarkers between women with and without GDM, and to explore the moderating effect of progression to type 2 diabetes (T2DM).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>We used electronic primary care healthcare records and linked hospital episode records of women who gave birth between 2001 and 2021. Each woman with GDM was matched to four women without GDM based on age at delivery and delivery date (\u00b13\u2009months). We fitted mixed\u2010effects multivariate linear models to map biomarker trajectories and extracted coefficients and 95% confidence intervals (CIs) for each year postpartum.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 43\u2009572 women diagnosed with GDM were matched with 174\u2009288 women without GDM in pregnancy. Across the 15\u2010year follow\u2010up, women with GDM weighed more (difference of 5.5\u2009kg [95% CI: 5.3 to 5.7]), had higher HbA1c concentrations (4.4\u2009mmol\/mol [95% CI: 4.3 to 4.5]), systolic and diastolic blood pressure (2.6\u2009mmHg [95% CI: 2.4 to 2.7] and 1.7\u2009mmHg [1.6 to 1.8] higher, respectively), and low\u2010density lipoprotein cholesterol (0.08 [95% CI: 0.06 to 0.10]). However, biomarkers increased at a slower rate during the follow\u2010up period among women with GDM, except for HbA1c (increase of 9.3\u2009mmol\/mol [95% CI: 8.8 to 9.7] and 2.3\u2009mmol\/mol [95% CI: 1.9 to 2.6] in the GDM and non\u2010GDM groups, respectively). Future Progression to type 2 diabetes moderated biomarker trajectories.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Differences in biomarker trajectories in the early postpartum present an opportunity for early risk stratification and targeted prevention among women with previous GDM.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.70994","type":"journal-article","created":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T01:16:20Z","timestamp":1782177380000},"page":"8254-8265","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Postpartum Body Weight and Cardiometabolic Biomarker Trajectories in Women With Gestational Diabetes: A Population\u2010Based Matched Cohort Study"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6458-4357","authenticated-orcid":false,"given":"Ruya","family":"Abdulsalam","sequence":"first","affiliation":[{"name":"Nuffield Department of Primary Care Health Sciences University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan A.","family":"Jebb","sequence":"additional","affiliation":[{"name":"Nuffield Department of Primary Care Health Sciences University of Oxford  Oxford UK"},{"name":"National Institutes for Health Research (NIHR) Oxford Biomedical Research Centre  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6063-3307","authenticated-orcid":false,"given":"Moscho","family":"Michalopoulou","sequence":"additional","affiliation":[{"name":"Nuffield Department of Primary Care Health Sciences University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Piernas","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology II, Faculty of Pharmacy; Centre for Biomedical Research Institute of Nutrition and Food Technology; Biosanitary Research Institute Ibs.Granada; University of Granada  Granada Spain"},{"name":"CIBER Physiopathology of Obesity and Nutrition (CIBEROBN) Instituto de Salud Carlos III  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Stevens","sequence":"additional","affiliation":[{"name":"Nuffield Department of Primary Care Health Sciences University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9301-7458","authenticated-orcid":false,"given":"Nerys M.","family":"Astbury","sequence":"additional","affiliation":[{"name":"Nuffield Department of Primary Care Health Sciences University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,22]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"NICE guideline N. Diabetes in Pregnancy: Management From Preconception to the Postnatal Period(2015)."},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc22-S002"},{"key":"e_1_2_10_4_1","unstructured":"UK D Causes of Gestational Diabetes 2023 https:\/\/www.diabetes.org.uk\/about\u2010diabetes\/gestational\u2010diabetes\/causes."},{"key":"e_1_2_10_5_1","unstructured":"Digital N National Gestational Diabetes Mellitus Audit 2025 https:\/\/digital.nhs.uk\/data\u2010and\u2010information\/clinical\u2010audits\u2010and\u2010registries\/gestational\u2010diabetes\u2010mellitus\u2010audit."},{"key":"e_1_2_10_6_1","unstructured":"ID Federation IDF Diabetes Atlas 11th edn. Brussels(2025)."},{"key":"e_1_2_10_7_1","unstructured":"Digital N National Gestational Diabetes Mellitus (GDM) Audit 2024\u201325(2025)."},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj-2021-067946"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina59122096"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0707943"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m1361"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2020.108625"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125\u2010019\u20104840\u20102"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.5768"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.15612"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsx.2024.103064"},{"issue":"1","key":"e_1_2_10_17_1","article-title":"Preterm Delivery and Incident Metabolic Syndrome: A 25\u2010Year Prospective Study of Cardia Women","volume":"129","author":"Catov J. 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