{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T04:39:01Z","timestamp":1792471141697,"version":"4.5.0"},"reference-count":29,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:00:00Z","timestamp":1785369600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:00:00Z","timestamp":1785369600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100020669","name":"F\u00e9d\u00e9ration Fran\u00e7aise des Diab\u00e9tiques","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020669","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004312","name":"Lilly","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004312","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000046","name":"Abbott Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000046","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004191","name":"Novo Nordisk","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004191","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021515","name":"Sanofi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100021515","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014592","name":"Insulet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014592","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016304","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016304","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015769","name":"Dexcom","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015769","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004719","name":"Lifescan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004719","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To estimate the societal costs of Type 1 diabetes (T1D) in France, including direct and indirect costs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>We conducted a descriptive retrospective cross\u2010sectional study on all adult patients (aged 18 and over) with T1D identified in the SFDT1 cohort and compared them to a matched cohort of patients without diabetes considering age, gender, deprivation status and geographical area. An Insurance claim data analysis was conducted for the year 2023 individually and then extrapolated to all of France. Costs were broken down by expense categories and insulin delivery devices.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The average individual societal cost of T1D in France in 2023 compared with the absence of diabetes was estimated at \u20ac9940 (\u20ac9340 when considering direct costs only). Nearly half of the identified costs were attributable to the use of medical devices. An analysis stratifying patients by treatment modality (closed\u2010loop, pump or multiple daily injections) highlighted the significant costs associated with the use of the most advanced technologies for delivering insulin (average costs were respectively \u20ac13\u2009557, \u20ac11\u2009062, and \u20ac7004, respectively). The total cost of T1D in France was estimated at between \u20ac1.59 and \u20ac1.79 billion in 2023 excluding undiagnosed cases and premature mortality associated with the disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our results suggest that the most advanced insulin delivery devices have a significant short\u2010term economic impact. Although this paper does not cover the research, model\u2010based studies do suggest that there are some advantages to using such devices, including potential future savings due to lower complication rates.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.71103","type":"journal-article","created":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T03:20:20Z","timestamp":1785468020000},"page":"9443-9449","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Economic Burden of Type 1 Diabetes in France"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8785-3385","authenticated-orcid":false,"given":"Emmanuel","family":"Cosson","sequence":"first","affiliation":[{"name":"Department of Endocrinology\u2010Diabetology\u2010Nutrition AP\u2010HP, Avicenne Hospital, Universit\u00e9 Paris 13, Sorbonne Paris Cit\u00e9, CRNH\u2010IdF, CSO\u2010IdF Nord  Bobigny France"},{"name":"Center of Research in Epidemiology and StatisticS (CRESS), Nutritional Epidemiology Research Team (EREN) Universit\u00e9 Sorbonne Paris Nord and Universit\u00e9 Paris Cit\u00e9, INSERM, INRAE, CNAM  Bobigny France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7333-0567","authenticated-orcid":false,"given":"Corinne","family":"Emery","sequence":"additional","affiliation":[{"name":"Cemka  Bourg\u2010la\u2010Reine France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elodie","family":"Torreton","sequence":"additional","affiliation":[{"name":"Cemka  Bourg\u2010la\u2010Reine France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7843-4608","authenticated-orcid":false,"given":"Bruno","family":"Detournay","sequence":"additional","affiliation":[{"name":"Cemka  Bourg\u2010la\u2010Reine France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8957-629X","authenticated-orcid":false,"given":"Bruno","family":"Verges","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Diabetology and Metabolic Diseases CHU Dijon  Dijon France"},{"name":"INSERM LNC\u2010UMR1231 University of Burgundy  Dijon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4378-0468","authenticated-orcid":false,"given":"Pierre\u2010Yves","family":"Benhamou","sequence":"additional","affiliation":[{"name":"Department of Endocrinology Grenoble University Hospital, Grenoble Alpes University, INSERM U1055, LBFA  Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3685-2523","authenticated-orcid":false,"given":"Maxime","family":"Brule","sequence":"additional","affiliation":[{"name":"Francophone Foundation for Diabetes Research  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8026-7826","authenticated-orcid":false,"given":"Laura","family":"Sablone","sequence":"additional","affiliation":[{"name":"Francophone Foundation for Diabetes Research  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5033-5966","authenticated-orcid":false,"given":"Guy","family":"Fagherazzi","sequence":"additional","affiliation":[{"name":"Deep Digital Phenotyping Research Unit, Department of Precision Health Luxembourg Institute of Health  Strassen Luxembourg"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7991-0741","authenticated-orcid":false,"given":"Jean Pierre","family":"Riveline","sequence":"additional","affiliation":[{"name":"Department of Diabetology and Endocrinology, Lariboisiere Hospital AP\u2010HP  Paris France"},{"name":"INSERM U1138 Immunity and Metabolism in Diabetes, ImMeDiab Team, Necker Enfants Malades Institute Paris Cit\u00e9 University  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc21\u20101752"},{"key":"e_1_2_10_2_2","unstructured":"Erratum in:Diabetes Care46 no.11(2023):2084 https:\/\/doi.org\/10.2337\/dc23\u2010er11."},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213\u20108587(22)00218\u20102"},{"key":"e_1_2_10_3_2","doi-asserted-by":"crossref","unstructured":"Erratum in:Lancet Diabetes & Endocrinology10 no.11(2022):e11 https:\/\/doi.org\/10.1016\/S2213\u20108587(22)00280\u20107.","DOI":"10.1016\/S2213-8587(22)00279-0"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2025.112277"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13300\u2010025\u201001781\u20100"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jval.2024.10.1344"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.5772\/intechopen.89895"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabet.2021.101306"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/pds.4233"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.respe.2017.05.004"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2008.09.031"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1201\/9780429258350"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.37737\/ace.22005"},{"key":"e_1_2_10_14_1","unstructured":"ScanSant\u00e9 \u201cR\u00e9f\u00e9rentiel national de co\u00fbts des prises en charge (ENC) \u201dhttps:\/\/www.scansante.fr\/applications\/donnees\u2010de\u2010couts."},{"key":"e_1_2_10_15_1","unstructured":"Eurostat \u201cLabour Cost Levels by NACE Rev. 2 Activity \u201dhttps:\/\/ec.europa.eu\/eurostat\/databrowser\/view\/lc_lci_lev\/default\/table?lang=en."},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13144005"},{"key":"e_1_2_10_17_1","unstructured":"OECD \u201cA System of Health Accounts 2011: Revised Edition \u201dhttps:\/\/www.oecd.org\/content\/dam\/oecd\/en\/publications\/reports\/2017\/03\/a\u2010system\u2010of\u2010health\u2010accounts\u20102011_g1g75c9d\/9789264270985\u2010en.pdf."},{"key":"e_1_2_10_18_1","unstructured":"French Health Ministry. Directorate for Research Studies Evaluation and Statistics (Direction de la recherche des \u00e9tudes de l'\u00e9valuation et des statistiques \u2010 DREES) \u201cLes d\u00e9penses de sant\u00e9 en 2023 R\u00e9sultats des comptes de la sant\u00e9 \u201dhttps:\/\/drees.solidarites\u2010sante.gouv.fr\/sites\/default\/files\/2025\u201002\/Les%20d%C3%A9penses%20de%20sant%C3%A9%20en%202023_MEL2ok.pdf."},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.70586"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S532553"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc24\u20101550"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2025"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.70302"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjdrc\u20102024\u2010004428"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgaf034"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2025.0100"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabet.2025.101721"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.2196\/86690"}],"container-title":["Diabetes, Obesity and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dom-pubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dom.71103","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dom-pubs.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/dom.71103","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dom-pubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dom.71103","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T03:51:52Z","timestamp":1792468312000},"score":1,"resource":{"primary":{"URL":"https:\/\/dom-pubs.onlinelibrary.wiley.com\/doi\/10.1111\/dom.71103"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,30]]},"references-count":29,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1111\/dom.71103"],"URL":"https:\/\/doi.org\/10.1111\/dom.71103","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/DOM.71103\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71103\/v3\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71103\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71103\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71103\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71103\/v1\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71103\/v2\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71103\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71103\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71103\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71103\/v3\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71103\/v3\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71103\/v3\/response1","asserted-by":"object"}]},"ISSN":["1462-8902","1463-1326"],"issn-type":[{"value":"1462-8902","type":"print"},{"value":"1463-1326","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,30]]},"assertion":[{"value":"2026-04-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}