{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T05:14:34Z","timestamp":1788412474488,"version":"build-2803163510"},"reference-count":30,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T00:00:00Z","timestamp":1785024000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T00:00:00Z","timestamp":1785024000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000329","name":"Novo Nordisk UK Research Foundation","doi-asserted-by":"publisher","award":["Novo Nordisk UK Research Fellowship 2022"],"award-info":[{"award-number":["Novo Nordisk UK Research Fellowship 2022"]}],"id":[{"id":"10.13039\/501100000329","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Research studies that screen and monitor children and young people (CYP) with early\u2010stage type 1 diabetes (T1D) are gaining momentum, but the views of healthcare professionals (HCP) on the ability to implement monitoring strategies in clinical practice remain unclear. This study aims to explore the perspectives of HCPs in the United Kingdom on monitoring CYP with early\u2010stage T1D in clinical care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Fifteen HCPs across the United Kingdom took part in a semi\u2010structured interview, with representation from across the paediatric diabetes multidisciplinary team. The perspectives of HCPs on monitoring CYP with early\u2010stage T1D for progression to clinical disease were explored. Data analysis was conducted using a thematic analysis approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Three themes were generated: (1) Uncertainty managing the early stages of T1D; (2) The need for guidance, training and consistent messaging; (3) Integrating monitoring into clinical care. Participants highlighted that knowledge gaps created uncertainty in their approach to monitoring. HCPs sought guidance and clear pathways to support their decision\u2010making on understanding the risk of progression associated with early\u2010stage T1D and which test to use when monitoring and communicating risk to families. HCPs were supportive of monitoring within clinical care but emphasised the need for expansion of clinical services to meet increased caseloads and upskilling the HCP workforce.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>HCPs would support the monitoring of CYP within a clinical care setting but highlight important barriers to implementation that need addressing before national rollout. This includes HCP education, clear pathways to ensure national guidance and standardisation of clinical practice, and expansion of clinical services.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.71141","type":"journal-article","created":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T02:50:26Z","timestamp":1785120626000},"page":"9326-9335","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A\n                    <scp>UK<\/scp>\n                    Healthcare Professional Perspective on the Implementation of Monitoring in Children and Young People With Early\u2010Stage Type 1 Diabetes: A Qualitative Study"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5815-7279","authenticated-orcid":false,"given":"Rabbi","family":"Swaby","sequence":"first","affiliation":[{"name":"Diabetes and Inflammation Laboratory, Centre for Human Genetics, Nuffield Department of Medicine, Bukhman Centre for Research Excellence in Type 1 Diabetes, NIHR Oxford Biomedical Research Centre University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Townson","sequence":"additional","affiliation":[{"name":"Centre for Trials Research Cardiff University  Cardiff UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel E. J.","family":"Besser","sequence":"additional","affiliation":[{"name":"Diabetes and Inflammation Laboratory, Centre for Human Genetics, Nuffield Department of Medicine, Bukhman Centre for Research Excellence in Type 1 Diabetes, NIHR Oxford Biomedical Research Centre University of Oxford  Oxford UK"},{"name":"Department of Paediatrics University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,26]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.70016"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.2337\/dbi20-0054"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc15-1419"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.6285"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/pedi.12541"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-023-05953-0"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.6.1399"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2021-321864"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11892-025-01612-3"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/dme.15131"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2024.111931"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.2337\/cd23-0057"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1155\/2024\/9927027"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(24)00238-9"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/dme.70178"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/dme.70069"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/1744987120927206"},{"key":"e_1_2_9_19_1","unstructured":"Microsoft \u201cDownload Microsoft Teams for Windows Desktop \u201d2024 accessed September 17 2024 https:\/\/www.microsoft.com\/en\u2010gb\/microsoft\u2010teams\/download\u2010app?msockid=3f25914f66086d941080826867ef6c3e."},{"key":"e_1_2_9_20_1","unstructured":"Lumivero \u201cNVivo\u2014The #1 Qualitative Data Analysis Software for 30\u2009Years \u201d2026 accessed March 3 2026 https:\/\/lumivero.com\/products\/nvivo\/."},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1191\/1478088706qp063oa"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACM.0000000000000388"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(23)00354-6"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-011144"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/dme.70077"},{"issue":"8","key":"e_1_2_9_26_1","first-page":"1276","article-title":"Consensus Guidance for Monitoring Individuals With Islet Autoantibody\u2013Positive Pre\u2010Stage 3 Type 1 Diabetes","volume":"47","author":"Phillip M.","year":"2024","journal-title":"Diabetes Care"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1159\/000543035"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc17-0166"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc24-2908"},{"key":"e_1_2_9_30_1","unstructured":"National Institute for Health and Care Excellence \u201cDiagnosis in Children and Young People 2025 \u201daccessed March 3 2026 https:\/\/cks.nice.org.uk\/topics\/diabetes\u2010type\u20101\/diagnosis\/diagnosis\u2010in\u2010children\u2010young\u2010people\/."},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/dme.70117"}],"container-title":["Diabetes, Obesity and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dom-pubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dom.71141","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dom-pubs.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/dom.71141","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dom-pubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dom.71141","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T04:21:34Z","timestamp":1788409294000},"score":1,"resource":{"primary":{"URL":"https:\/\/dom-pubs.onlinelibrary.wiley.com\/doi\/10.1111\/dom.71141"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,26]]},"references-count":30,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1111\/dom.71141"],"URL":"https:\/\/doi.org\/10.1111\/dom.71141","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/DOM.71141\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71141\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71141\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71141\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71141\/v1\/review2","asserted-by":"object"}]},"ISSN":["1462-8902","1463-1326"],"issn-type":[{"value":"1462-8902","type":"print"},{"value":"1463-1326","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,26]]},"assertion":[{"value":"2026-05-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}