{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T04:41:22Z","timestamp":1792384882030,"version":"4.4.0"},"reference-count":38,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To evaluate whether a community\u2010based personalised lifestyle intervention guided by intermittent continuous glucose monitoring (CGM) improves glycaemic and cardiometabolic outcomes in adults with type 2 diabetes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>In this multicentre, open\u2010label randomised trial, 180 adults with type 2 diabetes and pre\u2010randomisation HbA1c &gt;\u20097.0% were assigned 1:1 to the CGM\u2010guided intervention or usual community diabetes management and followed for 12\u2009months. The intervention combined FreeStyle Libre 2 use at baseline, after the Month 3 assessment and at Month 6 with personalised lifestyle guidance and supervised exercise concentrated in the first 3\u2009months. The primary outcome was HbA1c at Month 3, analysed using multiple\u2010imputation ANCOVA adjusted for baseline HbA1c and community site.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The primary analysis set included 171 participants. The adjusted intervention\u2010minus\u2010control difference in Month 3 HbA1c was \u22120.09 percentage points (95% CI, \u22120.38 to 0.21;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.573). Supportive complete\u2010data ANCOVA in 125 participants yielded a similar estimate of \u22120.12 percentage points (95% CI, \u22120.44 to 0.20;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.472). No significant between\u2010group HbA1c differences were observed at Months 6 or 12, and secondary outcomes showed no consistent benefit. Two Month 3 responder outcomes nominally favoured the intervention, but neither remained significant after multiplicity adjustment (both\n                      <jats:italic>q<\/jats:italic>\n                      \u2009=\u20090.104). Exploratory analyses identified no baseline subgroup with greater Month 3 benefit.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The intervention did not significantly improve glycaemic or cardiometabolic outcomes beyond usual community care. Whether more sustained feedback and engagement can improve effectiveness requires evaluation before routine implementation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>ChiCTR2400085258<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.71221","type":"journal-article","created":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T03:40:51Z","timestamp":1786592451000},"page":"10070-10080","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Community\u2010Based Personalised Lifestyle Intervention Guided by Intermittent Continuous Glucose Monitoring in Adults With Type 2 Diabetes: A Multicentre Randomised Controlled Trial"],"prefix":"10.1111","volume":"28","author":[{"given":"Yaqing","family":"Liu","sequence":"first","affiliation":[{"name":"School of Medicine and Health Management Tongji Medical College, Huazhong University of Science and Technology  Wuhan Hubei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3195-109X","authenticated-orcid":false,"given":"Shan","family":"Zheng","sequence":"additional","affiliation":[{"name":"School of Medicine and Health Management Tongji Medical College, Huazhong University of Science and Technology  Wuhan Hubei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zifu","family":"Yu","sequence":"additional","affiliation":[{"name":"Shandong Center for Disease Control and Prevention  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ran","family":"Zhao","sequence":"additional","affiliation":[{"name":"Shandong Center for Disease Control and Prevention  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Li","sequence":"additional","affiliation":[{"name":"Shandong Center for Disease Control and Prevention  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suyun","family":"Li","sequence":"additional","affiliation":[{"name":"Shandong Center for Disease Control and Prevention  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangxia","family":"Chen","sequence":"additional","affiliation":[{"name":"Shandong Center for Disease Control and Prevention  Jinan 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